208795

S-Methyl methanethiosulfonate

97%

• Synonym(s): S-Methyl thiomethanesulfonate, MMTS
• Linear Formula: CH₃SO₂SCH₃
• CAS Number: 2949-92-0
• Molecular Weight: 126.20
• Beilstein: 1446059
• EC Number: 220-970-0
• MDL number: MFCD00007565
• UNSPSC Code: 12352100
• PubChem Substance ID: 24852530
• NACRES: NA.22

Properties

• Assay: 97%
• form: liquid
• refractive index: n20/D 1.513 (lit.)
• bp: 69-71 °C/0.4 mmHg (lit.)
• solubility: DMF: soluble 1:1; chloroform: soluble 200 ul per mL, clear, faintly yellow-green; water: soluble 1:5
• density: 1.337 g/mL at 25 °C (lit.)
• functional group: disulfide
• SMILES string: CSS(C)(=O)=O
• InChI: 1S/C2H6O2S2/c1-5-6(2,3)4/h1-2H3
• InChI key: XYONNSVDNIRXKZ-UHFFFAOYSA-N

Description

General description

S-Methyl methanethiosulfonate is a reagent used to synthesize thiols and thioesters. Used as cross-linking agent to prepare polymer networks. Interaction of S-methyl methanethiosulfonate (MMTS) with dipalmitoylphosphatidylcholine (DPPC) bilayers has been investigated by FTIR and surface-enhanced Raman spectroscopy.

Application

S-Methyl methanethiosulfonate was used as sulfenylating agent for β-keto sulfoxides, methylene compounds, half-esters of malonic acids and aryl Grignard reagents. It was also used as a reagent to trap the natural thiol-disulfide state of the proteins.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): 188.6 °F - closed cup
• Flash Point(C): 87 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves