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199524

Sigma-Aldrich

Chlorophenol Red

indicator grade

Synonym(s):

3′,3′-Dichlorophenolsulfonaphthalein

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About This Item

Empirical Formula (Hill Notation):
C19H12Cl2O5S
CAS Number:
4430-20-0
Molecular Weight:
423.27
Beilstein:
354053
EC Number:
224-619-2
MDL number:
MFCD00005877
UNSPSC Code:
12171500
PubChem Substance ID:
24851922
NACRES:
NA.47

grade

indicator grade

Quality Level

200

form

powder, crystals or chunks

color

dark brown

pH

4.8-6.7, yellow to violet

solubility

95% ethanol: 10 mg/mL

λmax

572 nm

ε (extinction coefficient)

≥12000 at 295-301 nm in 0.1 M NaOH
≥45000 at 573-579 nm in 0.1 M NaOH
≥5000 at 368-374 nm in 0.1 M NaOH

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Oc1ccc(cc1Cl)C2(OS(=O)(=O)c3ccccc23)c4ccc(O)c(Cl)c4

InChI

1S/C19H12Cl2O5S/c20-14-9-11(5-7-16(14)22)19(12-6-8-17(23)15(21)10-12)13-3-1-2-4-18(13)27(24,25)26-19/h1-10,22-23H

InChI key

WWAABJGNHFGXSJ-UHFFFAOYSA-N

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Biochem/physiol Actions

Chlorophenol red is a pH indicator. It is used as an optical transducer of acetyl cholinesterase inhibition by the analytes. Chlorophenol red is also used to selectively determine chlorine dioxide in drinking water. It has been used in the novel assay to detect transformed protoplast-derived Zea mays colonies on Phosphinothricin (PPT).

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK7535
BCCH1315
BCCJ3706
BCCH5508
BCCG5218

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Julaluk Noiphung et al.
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Rationale: Saliva as a sample matrix is rapidly gaining interest for disease diagnosis and point-of-care assays because it is easy to collect (non-invasive) and contains many health-related biomarkers. However, saliva poses particular problems relative to more common urine and blood
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Two highly sensitive ELISAs for the specific detection of 17β-estradiol (E2) residues were developed, showing the limits of detection (LOD, a concentration at 15% inhibition of color development) of 0.04 ± 0.02 μg/L and 0.05 ± 0.03 μg/L. The average recovery rate of the river water
Ji Young Park et al.
Sensors (Basel, Switzerland), 20(5) (2020-03-08)
The food industry requires rapid and simple detection methods for preventing harm from pathogenic bacteria. Until now, various technologies used to detect foodborne bacteria were time-consuming and laborious. Therefore, we have developed an automated immunomagnetic separation combined with a colorimetric
Selection of transformed protoplast-derived Zea mays colonies with phosphinothricin and a novel assay using the pH indicator chlorophenol red
Kramer C
Planta, 190, 454-458 (1993)
Lilian L L Wong et al.
The Journal of biological chemistry, 293(41), 15777-15789 (2018-08-23)
The relaxin-3 neuropeptide activates the relaxin family peptide 3 (RXFP3) receptor to modulate stress, appetite, and cognition. RXFP3 shows promise as a target for treating neurological disorders, but realization of its clinical potential requires development of smaller RXFP3-specific drugs that
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