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161438

Sigma-Aldrich

2-Chloroanisole

98%

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About This Item

Linear Formula:
ClC6H4OCH3
CAS Number:
766-51-8
Molecular Weight:
142.58
EC Number:
212-167-9
MDL number:
MFCD00000557
UNSPSC Code:
12352100
PubChem Substance ID:
24849927
NACRES:
NA.22

Quality Level

100

Assay

98%

form

liquid

refractive index

n20/D 1.545 (lit.)

bp

195-196 °C (lit.)

density

1.123 g/mL at 25 °C (lit.)

functional group

chloro

SMILES string

COc1ccccc1Cl

InChI

1S/C7H7ClO/c1-9-7-5-3-2-4-6(7)8/h2-5H,1H3

InChI key

QGRPVMLBTFGQDQ-UHFFFAOYSA-N

General description

2-Chloroanisole undergoes acetylation with acetic anhydride over large pore zeolites to give 4-acetyl-2-chloroanisole.

Application

2-Chloroanisole was used in headspace solid-phase microextraction method for the determination of haloanisoles in wine and spirit samples.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

168.8 °F - closed cup

Flash Point(C)

76 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
STBK5692
STBJ7093
STBD2163V
02709LT
S34999

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Sigma-Aldrich

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Keith Smith et al.
Organic & biomolecular chemistry, 1(9), 1560-1564 (2003-08-21)
The acetylation of aryl ethers using acetic anhydride in the presence of zeolites under modest conditions in a solvent-free system gave the corresponding para-acetylated products in high yields. The zeolite can be recovered, regenerated and reused to give almost the
Natalia Campillo et al.
Journal of chromatography. A, 1210(2), 222-228 (2008-10-18)
A headspace solid-phase microextraction (HS-SPME) method for the determination of 12 haloanisoles in wine and spirit samples using gas chromatography with atomic emission detection (GC-AED) was developed. The different factors affecting the efficiency of the extraction were carefully optimized. The

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