143510
5-Hydroxyindole-2-carboxylic acid
≥96.5%
Synonym(s):
NSC 117338
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C9H7NO3
CAS Number:
Molecular Weight:
177.16
Beilstein:
153214
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Assay
≥96.5%
form
powder
mp
249 °C (dec.) (lit.)
solubility
chloroform/ethanol (1:1): soluble 50 mg/mL, clear to slightly hazy, yellow to brown
functional group
carboxylic acid
SMILES string
Oc1ccc2[nH]c(cc2c1)C(O)=O
InChI
1S/C9H7NO3/c11-6-1-2-7-5(3-6)4-8(10-7)9(12)13/h1-4,10-11H,(H,12,13)
InChI key
BIMHWDJKNOMNLD-UHFFFAOYSA-N
Looking for similar products? Visit Product Comparison Guide
General description
5-Hydroxyindole-2-carboxylic acid on oxidation with KMnO4 yields pyrrole-2,3,5-tricarboxylic acid.
Application
5-Hydroxyindole-2-carboxylic acid was used in HPLC-amperometric detection of serotonin in plasma, platelets and urine.
- Reactant for preparation of indole C5-O-substituted seco-cyclopropylindole analogs as potential anticancer agents
- Reactant for microwave combinatorial synthesis of indolic arylpiperazine derivatives as ligands for 5-HT1A, 5-HT2A, and 5-HT2C receptors
- Reactant for preparation of melanins as novel nature-inspired radioprotectors
- Reactant for preparation of 5-Hydroxyindole-2-carboxylic acid amides as histamine-3 receptor inverse agonists for the treatment of obesity
- Reactant for preparation of conformationally constrained peptidomimetic inhibitors of signal transducer and activator of transcription 3 (Stat3)
- Reactant for preparation of oxadiazole analogs as nonpeptidic SH2 inhibitors of tyrosine kinase ZAP-70
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
S Ito et al.
The Biochemical journal, 143(1), 207-217 (1974-10-01)
The reflecting material of the tapetum lucidum of the sea catfish (Arius felis) was chromatographed on Sephadex LH-20 in methanol-dimethyl sulphoxide-formic acid. Two components were present: one, showing an absorption maximum at 330nm, was tapetal pigment; the other, at 257nm
Zebin Lin et al.
Biomedical chromatography : BMC, 33(10), e4626-e4626 (2019-06-22)
N-Ethylpentylone (NEP) is a popular synthetic cathinone abused worldwide. To obtain more information about its pharmacokinetics and pharmacodynamics, a rapid, simple and sensitive liquid chromatography-tandem mass spectrometry method was developed for the determination of NEP, two important neurotransmitters, dopamine and
E Pussard et al.
Clinical chemistry, 42(7), 1086-1091 (1996-07-01)
We describe an isocratic liquid-chromatographic method with amperometric detection for determination of serotonin by rapid sample preparation. Platelet-poor plasma and platelets were injected after a single deproteinization step with perchloric acid. Addition of sodium borohydride to whole blood avoids oxidation
Yifeng Zeng et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1110-1111, 133-143 (2019-02-27)
Gut microbiota-host co-metabolites play an essential role in maintaining homeostasis, and their concentration changes are closely related to a variety of diseases. Developing a targeted metabolomics analytical platform for these co-metabolites will help to elucidate the relationship between intestinal flora
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service