12072
Benzamidine
≥95.0%
Synonym(s):
Benzenylamidine, Phenylamidine
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About This Item
Linear Formula:
C6H5C(=NH)NH2
CAS Number:
Molecular Weight:
120.15
Beilstein:
606020
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
≥95.0%
form
powder or crystals
functional group
amine
phenyl
SMILES string
NC(=N)c1ccccc1
InChI
1S/C7H8N2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H3,8,9)
InChI key
PXXJHWLDUBFPOL-UHFFFAOYSA-N
Gene Information
human ... F10(2159) , F2(2147) , PLAT(5327) , PLAU(5328) , PLG(5340) , PRSS1(5644)
Related Categories
Application
Benzamidine was used in the preparation of heparan sulfate-rich proteoglycan from mouse mammary epithelial cells. It has been used to prevent enzymatic degradation during the purification procedure of bovine factor XII (Hageman factor).
Biochem/physiol Actions
Benzamidine is an inhibitor of plasmin and has been used in the radioimmunoassay of glucagon in human plasma. It prevents the destruction of Thyrotropin-releasing hormone (TRH) added to whole blood in vitro before radioimmunoassay of TRH.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Purification and characterization of bovine coagulation factor XII (Hageman factor).
H Claeys et al.
European journal of biochemistry, 87(1), 69-74 (1978-06-01)
Hung-Wei Chang et al.
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Vaccinia mature virus requires A26 envelope protein to mediate acid-dependent endocytosis into HeLa cells in which we hypothesized that A26 protein functions as an acid-sensitive membrane fusion suppressor. Here, we provide evidence showing that N-terminal domain (aa1-75) of A26 protein
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Several focal adhesion proteins are known to cooperate with integrins to link the extracellular matrix to the actin cytoskeleton; as a result, many intracellular signaling pathways are activated and several focal adhesion complexes are formed. However, how these proteins function
Use of benzamidine as a proteolytic inhibitor in the radioimmunoassay of glucagon in plasma.
J W Ensinck et al.
The Journal of clinical endocrinology and metabolism, 35(3), 463-467 (1972-09-01)
Use of benzamidine to prevent the destruction of thyrotropin-releasing hormone (TRH) by blood.
S L Jeffcoate et al.
The Journal of clinical endocrinology and metabolism, 38(1), 155-157 (1974-01-01)
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