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115169

Sigma-Aldrich

Tetramethylthiourea

98%

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About This Item

Linear Formula:
(CH3)2NCSN(CH3)2
CAS Number:
Molecular Weight:
132.23
Beilstein:
1744916
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

form

solid

bp

245 °C (lit.)

mp

75-77 °C (lit.)

storage temp.

2-8°C

SMILES string

CN(C)C(=S)N(C)C

InChI

1S/C5H12N2S/c1-6(2)5(8)7(3)4/h1-4H3

InChI key

MNOILHPDHOHILI-UHFFFAOYSA-N

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General description

Tetramethylthiourea molecule shows crystallographic two-fold symmetry with weak hydrogen bond packing, which connects the molecules to form layers.

Application

Tetramethylthiourea forms BF3 adduct with tetramethylselenourea.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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I Neumcke et al.
Endocrinology, 140(2), 641-645 (1999-02-02)
The most important stimulus for the enhanced synthesis of erythropoietin (Epo) is a lowered O2 tension in the tissue. However, the mechanism by which an impaired O2 supply is transduced into appropriate Epo production is still not fully understood. Recently
Yefeng Tang et al.
Organic letters, 7(4), 593-595 (2005-02-12)
A Pauson-Khand type of conversion of enynes to bicyclic cyclopentenones employing the commercially available Co2(CO)8 and tetramethylthiourea (TMTU) as catalysts is described. This method allows a variety of enynes with diverse functional groups to be cyclized into cyclopentenones of interest.
Jin Dai et al.
American journal of respiratory cell and molecular biology, 29(3 Pt 1), 352-358 (2003-03-22)
There is evidence that chronic exposure to high levels of ambient particulate pollutants (PM) is associated with chronic airflow obstruction, but how this occurs is not known. We exposed rat tracheal explants to Ottawa urban air particles (ECH93) or diesel
Peter G Jones et al.
Acta crystallographica Section B, Structural science, crystal engineering and materials, 69(Pt 4), 405-413 (2013-07-23)
We have redetermined the known structures of (i) methylthiourea (MTU) and (ii) 1,1-dimethylthiourea (1,1-DMTU), and investigated the structure of 1,3-dimethylthiourea (1,3-DMTU), which was however severely disordered. We report the structures of crystalline adducts of (iii) MTU with morpholine (1:1), (iv)
A Shukla et al.
Cancer research, 61(5), 1791-1795 (2001-03-31)
Crystalline silica has been classified as a group 1 human carcinogen in the lung. However, its mechanisms of action on pulmonary epithelial cells which give rise to lung cancers are unclear. Using a nontransformed alveolar type II epithelial cell line

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