H0892
Anti-Hemocyanin (KLH) antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
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About This Item
Recommended Products
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
keyhole limpet
packaging
antibody small pack of 25 μL
technique(s)
indirect ELISA: 1:20,000
shipped in
ambient
storage temp.
−20°C
target post-translational modification
unmodified
General description
Hemocyanin is a large, multi-subunit respiratory protein present in arthropods and mollucs. They circulate extracellularly in hemolymph. Hemocyanins do not contain iron but bind oxygen at an active site containing copper atoms ligated by protein side chains.
Application
Anti-Hemocyanin (KLH) antibody produced in rabbit has been used in:
- immunocytochemistry{58
- }immunohistochemistry
- immunofluorescent staining
- immunoblotting
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunocytochemistry (1 paper)
Immunocytochemistry (1 paper)
Biochem/physiol Actions
Keyhole limpet hemocyanin has been used traditionally as a protein carrier for hapten-carrier conjugates in immunochemistry. Keyhole limpet hemocyanin (KLH) has been regarded as a superior carrier. Affinity isolated antibody to hemocyanin may be used as a control reagent for the preparation and immunization of hapten-carrier conjugates.
Physical form
Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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The Planorbid Snail Biomphalaria glabrata Expresses a Hemocyanin-Like Sequence in the Albumen Gland.
Janeth J Peña et al.
PloS one, 11(12), e0168665-e0168665 (2016-12-31)
The parasitic flatworm Schistosoma mansoni, causative agent of human intestinal schistosomiasis in South America, relies importantly on the freshwater snail Biomphalaria glabrata as intermediate host to achieve development of cercariae that infect humans. The recommendation from the World Health Organization
Dario Armando Leone et al.
Journal of immunology (Baltimore, Md. : 1950), 199(2), 531-546 (2017-06-14)
The lysosome-associated membrane protein (LAMP) family includes the dendritic cell endocytic receptors DC-LAMP and CD68, as well as LAMP-1 and LAMP-2. In this study we identify LAMP-1 (CD107a) and LAMP-2 (CD107b) on the surface of human monocyte-derived dendritic cells (MoDC)
Nuclear interleukin-33 is generally expressed in resting endothelium but rapidly lost upon angiogenic or proinflammatory activation
Kuchler AM, et al.
The American Journal of Pathology, 173(4), 1229-1242 (2008)
The murine IL-8 homologues KC, MIP-2, and LIX are found in endothelial cytoplasmic granules but not in Weibel-Palade bodies
Hol J, et al.
Journal of Leukocyte Biology, 87(3), 501-508 (2010)
Surface LAMP-2 is an endocytic receptor that diverts antigen internalized by human dendritic cells into highly immunogenic exosomes
Leone DA, et al.
Journal of immunology (Baltimore, Md. : 1950), 199(2), 531-546 (2017)
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