E5139

DL-Ethionine

≥95% (TLC)

• Synonym(s): DL-2-Amino-4-(ethylthio)butyric acid
• Linear Formula: C₂H₅SCH₂CH₂CH(NH₂)COOH
• CAS Number: 67-21-0
• Molecular Weight: 163.24
• Beilstein: 1722529
• EC Number: 200-647-0
• MDL number: MFCD00063102
• UNSPSC Code: 12352209
• PubChem Substance ID: 24894606
• NACRES: NA.26

Properties

• product name: DL-Ethionine, ≥95% (TLC)
• Assay: ≥95% (TLC)
• form: powder
• color: white to off-white
• mp: 269 °C
• application(s): cell analysis
• storage temp.: −20°C
• SMILES string: CCSCCC(N)C(O)=O
• InChI: 1S/C6H13NO2S/c1-2-10-4-3-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)
• InChI key: GGLZPLKKBSSKCX-UHFFFAOYSA-N

Description

Application

• Superoxide dismutase activity as a measure of hepatic oxidative stress in cattle following ethionine administration.: This study evaluates the hepatic oxidative stress in cattle induced by ethionine administration by measuring superoxide dismutase activity. The findings suggest a significant oxidative response, highlighting the role of DL-Ethionine in studying liver oxidative mechanisms (Abd Ellah et al., 2009).

Biochem/physiol Actions

DL-Ethionine is a racemic mixture of the anti-methylation agent L-Ethionine and its enantiomer D-Ethionine. DL-Ethionine is used as a dietary supplement to accelerate cholangiocarcinogenesis in vivo. DL-Ethionine is used to induce oxidative stress in liver to study the levels and activities of anti-oxidative enzymes and compounds such as glutathione.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves