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Key Documents

C0465000

Carbimazole

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

2,3-Dihydro-3-methyl-2-thioxo-1H-imidazole-1-carboxylic acid ethyl ester

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About This Item

Empirical Formula (Hill Notation):
C7H10N2O2S
CAS Number:
22232-54-8
Molecular Weight:
186.23
MDL number:
MFCD00027421
UNSPSC Code:
41116107
NACRES:
NA.24
Pricing and availability is not currently available.

grade

pharmaceutical primary standard

API family

carbimazole

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

S=[c]1[n](cc[n]1C(=O)OCC)C

InChI

1S/C7H10N2O2S/c1-3-11-7(10)9-5-4-8(2)6(9)12/h4-5H,3H2,1-2H3

InChI key

CFOYWRHIYXMDOT-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Carbimazole EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Sarah M A Caney
Journal of feline medicine and surgery, 15(6), 494-502 (2013-04-18)
Hyperthyroidism is the most common feline endocrinopathy. Treatment options comprise anti-thyroid medication, iodine-restricted diet, surgical thyroidectomy and radioiodine. One hundred and eleven owners of hyperthyroid cats completed a detailed survey asking about their experiences and views on the management of
E Couderc et al.
Annales de dermatologie et de venereologie, 140(5), 382-385 (2013-05-15)
Localized myxoedema is a rare dermopathy in patients with Graves' disease. The pretibial area is the most commonly affected region but herein we present a case of myxoedema of the big toe. A 44-year-old male with Graves' disease ongoing for
Pinaki Dutta et al.
The Indian journal of medical research, 136(2), 242-248 (2012-09-11)
Hyperthyroidism is associated with increased food intake, energy expenditure and altered body composition. This study was aimed to evaluate the role of adipocytokines in weight homeostasis in patients with hyperthyroidism. Patients (n=27, 11men) with hyperthyroidism (20 Graves' disease, 7 toxic
Thomas A Mavrakanas et al.
Renal failure, 35(3), 414-417 (2013-01-25)
Anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis is a rare complication of antithyroid drug use that was first described with propylthiouracil. We describe an ANCA-associated rapidly progressive glomerulonephritis in a patient treated with carbimazole during 6 months for Graves disease that resulted in
Nishikant Damle et al.
Journal of pediatric endocrinology & metabolism : JPEM, 24(11-12), 1051-1054 (2012-02-09)
Autonomously functioning thyroid nodules (AFTN) are extremely rare in children. Malignancy may be rarely found in hyperfunctioning 'hot' nodules in adults. However, there are limited reports of AFTNs in young children presenting as or developing malignancy in future. We report
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