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34004

Supelco

Ipronidazole-OH

VETRANAL®, analytical standard

Synonym(s):

2-(1-Methyl-5-nitro-1H-imidazol-2-yl)propan-2-ol, Hydroxy-ipronidazole, IPZOH

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About This Item

Empirical Formula (Hill Notation):
C7H11N3O3
CAS Number:
Molecular Weight:
185.18
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

Cn1c(cnc1C(C)(C)O)[N+]([O-])=O

InChI

1S/C7H11N3O3/c1-7(2,11)6-8-4-5(9(6)3)10(12)13/h4,11H,1-3H3

InChI key

DTHPMNDYKOSVFR-UHFFFAOYSA-N

General description

Ipronidazole-OH is a metabolite of nitroimidazole antibiotics, used in veterinary medicine to combat anaerobic bacterial and parasitic infections.

Application

Ipronidazole-OH may be used as a reference standard in the determination of nitroimidazole drug and its corresponding hydroxy metabolites in aquaculture tissue by ultra-high performance liquid chromatography coupled to tandem mass spectrometry.
Ipronidazole-OH may be used as an analytical reference standard for the determination of the analyte in:
  • Cosmetics using high-performance liquid chromatography coupled to electrospray ionization-tandem mass spectrometry (HPLC-ESI-MS/MS).
  • Aquaculture tissue using ultra high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Recommended products

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Description
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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Determination of nitroimidazole residues in aquaculture tissue using ultra high performance liquid chromatography coupled to tandem mass spectrometry.
Gadaj A, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 960(6), 105-115 (2014)
Simultaneous determination of 15 nitroimidazoles in cosmetics by HPLC coupled with electrospray ionization-tandem mass spectrometry.
Meng S-X, et al.
Journal of AOAC (Association of Official Analytical Chemists) International, 97(6), 1538-1545 (2014)
Kamila Mitrowska et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 34(4), 573-581 (2016-11-15)
Nitroimidazoles are not authorised for the treatment of honey bees in the European Union. However, they can be found in honey largely because they are illegally used in apiculture for the treatment of Nosema. The aim of the study was
Simone Moretti et al.
Analytica chimica acta, 1032, 56-67 (2018-08-26)
A multiclass screening method to detect fifty-three forbidden substances by liquid-chromatography coupled to hybrid high-resolution mass spectrometry (LC-Q-Orbitrap) was developed and validated in bovine bile and urine. Eight classes of compounds were included in the method's scope (β-agonists, corticosteroids, nitroimidazoles
Chengfei Wang et al.
Food chemistry, 334, 127598-127598 (2020-07-25)
A multi-residue method has been developed for the identification and quantification of 78 compounds from seven different classes of veterinary drugs in eggs. This method was based on dispersive solid phase extraction where mixed-mode cation exchange sorbent was used to

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