T4930
Anti-Thrombopoietin antibody produced in goat
affinity isolated antibody, lyophilized powder
Synonym(s):
Anti-TPO
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About This Item
biological source
goat
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
mouse
technique(s)
indirect ELISA: suitable
neutralization: suitable
western blot: suitable
UniProt accession no.
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
mouse ... Thpo(21832)
Related Categories
General description
This antibody will neutralize the biological activity of recombinant mouse TPO. By ELISA, the antibody shows <15% cross-reactivity with recombinant human TPO.
Immunogen
recombinant mouse TPO.
Biochem/physiol Actions
Thrombopoietin is a humoral growth factor that is synthesized in the liver and regulates the proliferation and maturation of megakaryocytes, and production of platelets. It modulates the response of platelets to various stimuli by regulating the homeostatic potential.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 5% trehalose.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Certificates of Analysis (COA)
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Bernhard Wörmann
Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie, 40(5), 319-325 (2013-11-26)
Thrombocytopenia is a common hematologic disorder. Stimulation of thrombopoiesis may reduce the risk for thrombocytopenia-induced bleeding, prevent severe thrombocytopenia, and reduce the need for platelet transfusion. The key cytokine is thrombopoietin (TPO). It regulates proliferation and maturation of megakaryocytes as
Enrico Lupia et al.
Mediators of inflammation, 2012, 390892-390892 (2012-05-12)
Thrombopoietin (TPO) is a humoral growth factor originally identified for its ability to stimulate the proliferation and differentiation of megakaryocytes. In addition to its actions on thrombopoiesis, TPO directly modulates the homeostatic potential of mature platelets by influencing their response
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