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SML2570

Sigma-Aldrich

NSC 146109 hydrochloride

≥98% (HPLC)

Synonym(s):

(10-Methyl-9-anthracenyl) methyl carbamimidothioic acid ester hydrochloride, NSC146109 hydrochloride, XI-011 hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C17H16N2S · HCl
CAS Number:
59474-01-0
Molecular Weight:
316.85
MDL number:
MFCD09878281
UNSPSC Code:
12352200
NACRES:
NA.77

Assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

InChI

1S/C17H16N2S.ClH/c1-11-12-6-2-4-8-14(12)16(10-20-17(18)19)15-9-5-3-7-13(11)15;/h2-9H,10H2,1H3,(H3,18,19);1H

InChI key

VIBMUYOXJUCEMA-UHFFFAOYSA-N

Biochem/physiol Actions

NSC146109 is a potent activator of p53 that selectively inhibits growth of transformed cells without genotoxicity. NSC146109 activates p53 by inhibition of MDMX expression.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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