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Key Documents

RAB1652

Sigma-Aldrich

Human PSP94 ELISA

for serum, plasma and cell culture supernatants

Synonym(s):

β-Microseminoprotein, Beta-microseminoprotein , IGBF, Immunoglobulin-binding factor, Prostate secretory protein of 94 amino acids

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

human

technique(s)

ELISA: suitable

input

sample type cell culture supernatant(s)
sample type plasma
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... MSMB(4477)

Related Categories

General description

The prostate secretory protein of 94 amino acids (PSP94), which is secreted by the prostate gland, is a small, cysteine-rich, and non-glycosylated protein. It is found abundantly in prostatic secretions and is a primary constituent of human semen. Lower expression of the PSP94 gene is observed in prostate cancer. PSP94 acts as a tumor suppressor and curbs metastasis. It also acts as an inhibitor of sperm motility and sperm acrosome reaction. The PSP94 gene is located on the human chromosome at 10q11.22.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Other Notes

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

Pictograms

Corrosion
GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Bhakti R Pathak et al.
Asian journal of andrology, 12(5), 677-689 (2010-08-03)
The prostate secretory protein of 94 amino acids (PSP94) has been shown to interact with cysteine-rich secretory protein 3 (CRISP-3) in human seminal plasma. Interestingly, PSP94 expression is reduced or lost in the majority of the prostate tumours, whereas CRISP-3
Ashwani Kumar et al.
Journal of molecular biology, 397(4), 947-956 (2010-02-27)
Several recent genome-wide association studies have linked the human MSMB gene, encoding prostate secretory protein of 94 residues (PSP94), with prostate cancer susceptibility. PSP94 is one of the most abundant proteins from prostatic secretions and a primary constituent of human
Zhaohui Du et al.
International journal of cancer, 146(7), 1819-1826 (2019-06-22)
Latinos represent <1% of samples analyzed to date in genome-wide association studies of cancer. The clinical value of genetic information in guiding personalized medicine in populations of non-European ancestry will require additional discovery and risk locus characterization efforts across populations.

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