K3628

Kininogen, low molecular weight from human plasma

≥95% (SDS-PAGE), lyophilized powder

• Synonym(s): LMW kininogen
• MDL number: MFCD00131428
• UNSPSC Code: 12352200
• NACRES: NA.32

Properties

• biological source: human plasma
• Quality Level: 200
• Assay: ≥95% (SDS-PAGE)
• form: lyophilized powder
• mol wt: 64000 Da
• UniProt accession no.: P01042
• shipped in: dry ice
• storage temp.: −20°C
• Gene Information: human ... KNG1 (includes EG:3827)

Description

Application

Kininogen, low molecular weight from human plasma has been used to study rMASP-1 (recombinant mannose-binding lectin-associated serine protease 1)-mediated cleavage of LK (low molecular weight kininogen).[1] It has been used as a standard for protein identification in milk-proteomics study.[2]

Biochem/physiol Actions

Extracellular cysteine proteinase inhibitor.

LMW kininogen is a major extracellular cysteine proteinase inhibitor. Tissue kallikrein releases bradykinin, a potent bronchoconstrictor and vasoactive agent, from both HMW and LMY kininogen.

Physical form

Lyophilized from a solution in sodium acetate and sodium chloride.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves