F5884
α-L-Fucosidase from bovine kidney
ammonium sulfate suspension, ≥2.0 units/mg protein (biuret)
Synonym(s):
α-L-Fucoside fucohydrolase
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
MDL number:
UNSPSC Code:
12352204
NACRES:
NA.32
Recommended Products
biological source
bovine kidney
form
ammonium sulfate suspension
specific activity
≥2.0 units/mg protein (biuret)
mol wt
210-220 kDa (Subunits: 55-60 kDa)
foreign activity
α-mannosidase and β-galactosidase ≤0.1%
β-N-acetylglucosaminidase ≤0.2%
shipped in
wet ice
storage temp.
2-8°C
General description
α-L-fucosidases is a liposomal enzyme, which belongs to glycosyl hydrolases family.
Application
α-L-fucosidase from bovine kidney has been used:
- to study their ability to alter primary cell transduction
- to examine the role of fucose residues of cell surface glycans in adhesion
- to investigate its role during fertilization
Biochem/physiol Actions
α-L-fucosidases degrades fucose-containing fucoglycoconjugates and breaks fucosidic bonds in oligosaccharides and glycoconjugates. It acts as a tumor marker for hepatic and colorectal cancer. α-L-fucosidase exhibits transglycosylation property.
Unit Definition
One unit will hydrolyze 1.0 μmole of p-nitrophenyl α-L-fucoside to p-nitrophenol and L-fucose per min at pH 5.5 at 25°C.
Physical form
Suspension in 3.2 M (NH4)2SO4, 10 mM NaH2PO4 10 mM citrate, pH 6.0
substrate
Product No.
Description
Pricing
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
Novel alpha-l-fucosidases from a soil metagenome for production of fucosylated human milk oligosaccharides
Lezyk M, et al.
PLoS ONE, 11(1), e0147438-e0147438 (2016)
Human alpha-L-fucosidase-1 attenuates the invasive properties of thyroid cancer
Vecchio G, et al.
Testing, 8(16), 27075-27075 (2017)
Directed evolution of the alpha-L-fucosidase from Thermotoga maritima into an alpha-L-transfucosidase
Osanjo G, et al.
Biochemistry, 46(4), 1022-1033 (2007)
alpha-l-Fucosidase enhances capacitation-associated events in porcine spermatozoa
Romero-Aguirregomezcorta J, et al.
The Veterinary Journal, 203(1), 109-114 (2015)
Alline R Pacheco et al.
Nature, 492(7427), 113-117 (2012-11-20)
The mammalian gastrointestinal tract provides a complex and competitive environment for the microbiota. Successful colonization by pathogens requires scavenging nutrients, sensing chemical signals, competing with the resident bacteria and precisely regulating the expression of virulence genes. The gastrointestinal pathogen enterohaemorrhagic
Articles
Instructions for working with enzymes supplied as ammonium sulfate suspensions
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service