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F5506

Sigma-Aldrich

Freund′s Adjuvant, Incomplete

liquid

Synonym(s):

FICA

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46

form

liquid

Quality Level

300

color

faintly yellow to yellow

storage temp.

2-8°C

Application

Freund′s Adjuvants may be used to produce water-in-oil emulsions of immunogens. Antigens in water-in-oil emulsions stimulate high and long-lasting antibody responses which can be attributed to the slow release of antigen.
Freund′s adjuvant (incomplete) lacks the Mycobacteria found in Complete Freund′s Adjuvant so it minimizes the side-effects.Freund′s Adjuvant, Incomplete is used for boost injections. It was used to emulsify antigens that are injected into animals to produce monoclonal antibodies from the antiserum.

Other Notes

Each mL contains 0.85 mL paraffin oil and 0.15 mL mannide monooleate.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Product No.
Description
Pricing

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Stephan Culemann et al.
Nature, 572(7771), 670-675 (2019-08-09)
Macrophages are considered to contribute to chronic inflammatory diseases such as rheumatoid arthritis1. However, both the exact origin and the role of macrophages in inflammatory joint disease remain unclear. Here we use fate-mapping approaches in conjunction with three-dimensional light-sheet fluorescence
Alan Gillett et al.
PloS one, 4(11), e7773-e7773 (2009-11-17)
Multiple Sclerosis (MS) is a chronic inflammatory disease causing demyelination and nerve loss in the central nervous system. Experimental autoimmune encephalomyelitis (EAE) is an animal model of MS that is widely used to investigate complex pathogenic mechanisms. Transcriptional control through
Elisabeth J M Huijbers et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 24(11), 4535-4544 (2010-07-17)
Monoclonal antibody-based therapies have made an important contribution to current treatment strategies for cancer and autoimmune disease. However, the cost for these new drugs puts a significant strain on the health-care economy, resulting in limited availability for patients. Therapeutic vaccination
J Ziebuhr et al.
Journal of virology, 69(7), 4331-4338 (1995-07-01)
The RNA polymerase gene of human coronavirus (HCV) 229E encodes a large polyprotein that contains domains with motifs characteristic of both papain-like cysteine proteinases and proteinases with homology to the 3C proteinase of picornaviruses. In this study, we have, first
Katrine Hygum et al.
PloS one, 6(5), e20638-e20638 (2011-06-10)
In humans, the cobalamin (Cbl) -binding protein transcobalamin (TC) transports Cbl from the intestine and into all the cells of the body, whereas the glycoprotein haptocorrin (HC), which is present in both blood and exocrine secretions, is able to bind
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