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Ergtoxin Peptide

Name: Ergtoxin Peptide
Brand: SIGMA

>98% (HPLC), lyophilized powder, recombinant, expressed in E. coli

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About This Item

UNSPSC Code:

12352202

NACRES:

NA.32

MDL number:

MFCD01742062

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Product Name

Ergtoxin from Centruroides noxius (Scorpion), recombinant, expressed in E. coli, >98% (HPLC), lyophilized powder

recombinant

expressed in E. coli

Quality Level

200

assay

>98% (HPLC)

form

lyophilized powder

mol wt

apparent mol wt ~4.7 kDa by SDS-PAGE

solubility

aqueous buffer: soluble

storage temp.

−20°C

SMILES string

N%16%15[C@@](O[C@](C%16=O)(NC(=O)[C@H]%19CN([C@@H]%20Cc%21c%22c([nH]c%21)cccc%22C%20=C%19)C)C(C)C)([C@H]%17N(CCC%17)C(=O)[C@@H]%15Cc%18ccccc%18)O.N98[C@@](O[C@](C9=O)(NC(=O)[C@H]%11CN([C@@H]%12Cc%13c%14c([nH]c%13)cccc%14C%12=C%11)C)C(C)C)([C@H]%10N(CCC%10

InChI

1S/C35H39N5O5.C32H41N5O5.C31H39N5O5/c1-20(2)34(37-31(41)23-16-25-24-11-7-12-26-30(24)22(18-36-26)17-27(25)38(3)19-23)33(43)40-28(15-21-9-5-4-6-10-21)32(42)39-14-8-13-29(39)35(40,44)45-34;1-17(2)12-25-29(39)36-11-7-10-26(36)32(41)37(25)30(40)31(42-32,18(3)

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This Item	V3638	B2929	P5739
Sigma-Aldrich E9904 Ergtoxin from Centruroides noxius (Scorpion)	Sigma-Aldrich V3638 Vascular Endothelial Growth Factor 164 from rat	Sigma-Aldrich B2929 B-Lymphocyte Chemoattractant human	Sigma-Aldrich P5739 Placenta Growth Factor-2 from mouse
recombinant expressed in E. coli	recombinant expressed in NSO cells	recombinant expressed in E. coli	recombinant expressed in baculovirus infected Sf21 cells
assay >98% (HPLC)	assay >95% (SDS-PAGE)	assay ≥95% (SDS-PAGE)	assay >97% (SDS-PAGE)
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
form lyophilized powder	form lyophilized powder	form lyophilized powder	form lyophilized powder
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
mol wt apparent mol wt ~4.7 kDa by SDS-PAGE	mol wt dimer 50 kDa by SDS-PAGE, monomer 25 kDa by SDS-PAGE	mol wt apparent mol wt 8.7 kDa by SDS-PAGE (reducing)	mol wt ~38 kDa by SDS-PAGE

Biochem/physiol Actions

A novel ERG1 (K_V11.1) K⁺ channel blocker

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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A large number of novel Ergtoxin-like genes and ERG K+-channels blocking peptides from scorpions of the genus Centruroides.

Miguel Corona et al.

FEBS letters, 532(1-2), 121-126 (2002-12-03)

Twenty-three novel sequences similar to Ergtoxin (ErgTx) were obtained by direct sequencing of peptides or deduced from gene cloned using cDNAs of venomous glands of Centruroides (C.) elegans, C. exilicauda, C. gracilis, C. limpidus limpidus, C. noxius and C. sculpturatus.

Global Trade Item Number

SKU	GTIN
E9904-10UG	04061833384695
E9904-5UG	04061833476437

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