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Key Documents

D2289

Sigma-Aldrich

Dermenkephalin

≥97% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C44H62N10O10S2
CAS Number:
Molecular Weight:
955.15
UNSPSC Code:
12352200

Assay

≥97% (HPLC)

storage temp.

−20°C

Amino Acid Sequence

Tyr-D-Met-Phe-His-Leu-Met-Asp-NH2

Biochem/physiol Actions

Opioid peptide with selective affinity for δ-receptors

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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K Jhamandas et al.
Peptides, 27(5), 953-963 (2006-03-07)
Neuropeptide FF and related synthetic amidated peptides have been shown to elicit sustained anti-nociceptive responses and potently augment spinal anti-nociceptive actions of spinal morphine in tests of thermal and mechanical nociception. Recent studies have described the occurrence of another octapeptide
Deltorphin analogs restricted via a urea bridge: structure and opioid activity.
J Ciarkowski et al.
Advances in experimental medicine and biology, 611, 491-492 (2009-04-30)
Anna Capasso
Current medicinal chemistry, 15(24), 2518-2526 (2008-10-16)
The possible role of PGs and NO in the development of S&W of DBA/2J mice was investigated by evaluating the effects of dexamethasone, indometacin, mifepristone plus dexamethasone on the S&W, as well as of L-NAME both on the S&W in
Constance Auvynet et al.
European journal of cell biology, 85(1), 25-34 (2005-12-24)
The dermal glands of the South American hylid frog Phyllomedusa bicolor synthesize and expel huge amounts of cationic, alpha-helical, 24- to 33-residue antimicrobial peptides, the dermaseptins B. These glands also produce a wide array of peptides that are similar to
Jolanta H Kotlinska et al.
Behavioural pharmacology, 21(7), 638-648 (2010-08-24)
The aim of this study was to investigate whether the δ-opioid receptors are involved in the rewarding and reinstatement effect of cocaine in the conditioned place preference (CPP) test. Male Wistar rats were conditioned with cocaine (5 mg/kg) or saline in

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