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C3355

Coelenterazine hcp

≥95% (HPLC), solid

Synonym(s):

CLZN-hcp

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About This Item

Empirical Formula (Hill Notation):
C25H25N3O2
CAS Number:
123437-32-1
Molecular Weight:
399.48
UNSPSC Code:
12352204
PubChem Substance ID:
24892609
NACRES:
NA.83
MDL number:
MFCD03453204
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Product Name

Coelenterazine hcp, solid

assay

≥95% (HPLC)

Quality Level

200

form

solid

solubility

methanol: 1 mg/mL, clear, yellow to orange

storage temp.

−20°C

SMILES string

Oc1ccc(cc1)C2=CN3C(=O)C(Cc4ccccc4)=NC3=C(CC5CCCC5)N2

InChI

1S/C25H25N3O2/c29-20-12-10-19(11-13-20)23-16-28-24(21(26-23)14-17-8-4-5-9-17)27-22(25(28)30)15-18-6-2-1-3-7-18/h1-3,6-7,10-13,16-17,26,29H,4-5,8-9,14-15H2

InChI key

YEGCUOQUFAXCMK-UHFFFAOYSA-N

General description

Coelenterazine hcp is a semisynthetic analog of coelenterazine.

Application

Coelenterazine hcp has been used:
  • as a component of coelenterazine reagent in the reporter assay
  • in the purification of Renilla luciferase-labeled Annexin V
  • in evaluating the activity of aequorin in Escherichia coli

Biochem/physiol Actions

Coelenterazine hcp has 190 times higher luminescence intensity than native coelenterazine and a faster response time than native coelenterazine.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SLCM8639
SLBV5390
SLBT6815
SLBS6908
SLBS1209V

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Mehdi Zeinoddini et al.
Photochemistry and photobiology, 86(5), 1071-1075 (2010-07-29)
An aequorin-based Escherichia coli strain JM109 biosensor was constructed and characterized for its potential to detect toluene and related compounds in aqueous solutions. The biosensor was constructed based on a PGL2 plasmid carrying the lower pathway promoter (Pu) of the
Yao Cheng et al.
Plant & cell physiology, 59(5), 978-988 (2018-02-13)
Seed germination is sensitive to salt stress. ABA and Ca2+ are involved in the regulation of seed germination under salt stress. Ca2+ influx mediated by glutamate receptors (GLRs) plays important roles in many physiological processes in plants. Here, we investigated
Sarah E Webb et al.
Molecular reproduction and development, 82(7-8), 563-586 (2014-01-03)
In this review, we take a retrospective look at the discovery and utilization of the Ca(2+) -sensitive bioluminescent protein complex, aequorin. We do consider the contribution it has made to our understanding of the natural phenomenon of bioluminescence, but it
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Global Trade Item Number

SKUGTIN
C3355-50UG04061833384183
C3355-25UG04061831157604