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Sigma-Aldrich

Sodium stearate

≥88% fatty acids (as stearic acid) basis, powder

Synonym(s):

Octadecanoic acid sodium salt, Stearic acid sodium salt

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About This Item

Linear Formula:
CH3(CH2)16COONa
CAS Number:
822-16-2
Molecular Weight:
306.46
Beilstein:
3576813
EC Number:
212-490-5
MDL number:
MFCD00036404
UNSPSC Code:
12352211
PubChem Substance ID:
57648172

Assay

≥88% fatty acids (as stearic acid) basis

form

powder

impurities

≤0.2% free alkali (as NaOH)
≤8% Na

loss

≤2.5% loss on drying, 105 °C

lipid type

fatty acid modified lipids

SMILES string

[Na+].CCCCCCCCCCCCCCCCCC([O-])=O

InChI

1S/C18H36O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2-17H2,1H3,(H,19,20);/q;+1/p-1

InChI key

RYYKJJJTJZKILX-UHFFFAOYSA-M

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Biochem/physiol Actions

Stearic acid induces ER stress and cell death via effects on ER luminal calcium stores in H4IIE liver cells and primary hepatocytes .

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Chiara Parlati et al.
Pharmaceutical research, 26(5), 1084-1092 (2009-02-03)
Tobramycin microparticulate powders containing the hydrophobic adjunct sodium stearate were studied for their use as pulmonary formulations in dry powder inhalers. Spray-dried powders were characterized in terms of particle size distribution, morphology, crystallinity, drug dissolution rate, toxicity on epithelial lung
Solvent-induced crystal morphology transformation in a ternary soap system: sodium stearate crystalline fibers and platelets.
Liang J, et al.
Langmuir, 17(21), 6447-6454 (2001)
Sodium stearate-catalyzed multicomponent reactions for efficient synthesis of spirooxindoles in aqueous micellar media.
Wang L-M, et al.
Tetrahedron, 66(1), 339-343 (2010)
A Phase Rule Study of the System Sodium Stearate-Water.
McBain JW, et al.
The Journal of Physical Chemistry, 44(9), 1013-1024 (1940)
Yuren Wei et al.
Molecular and cellular biochemistry, 331(1-2), 31-40 (2009-05-16)
Chronic exposure to elevated free fatty acids, in particular long chain saturated fatty acids, provokes endoplasmic reticulum (ER) stress and cell death in a number of cell types. The perturbations to the ER that instigate ER stress and activation of
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