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Daidzin

analytical standard

Synonym(s):

4′,7-Dihydroxyisoflavone 7-glucoside, Daidzein 7-glucoside, Daidzein-7-O-β-D-glucopyranoside

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About This Item

Empirical Formula (Hill Notation):
C21H20O9
CAS Number:
Molecular Weight:
416.38
Beilstein:
59741
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

OC[C@H]1O[C@@H](Oc2ccc3C(=O)C(=COc3c2)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C21H20O9/c22-8-16-18(25)19(26)20(27)21(30-16)29-12-5-6-13-15(7-12)28-9-14(17(13)24)10-1-3-11(23)4-2-10/h1-7,9,16,18-23,25-27H,8H2/t16-,18-,19+,20-,21-/m1/s1

InChI key

KYQZWONCHDNPDP-QNDFHXLGSA-N

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General description

Daidzin is a plant isoflavone glycoside and a potent inhibitor of human mitochondrial aldehyde dehydrogenase (ALDH-I).

Application

Daidzin may be used as a reference standard in the determination of daidzin in the root of Pueraria lobate using high-performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Daidzin was the most potent isoflavone glycoside tested in modulating differentiation of bone marrow stromal cells toward osteoblasts and away from adipocytes.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Determination of puerarin, daidzin and daidzein in root of Pueraria lobata of different origin by HPLC.
SWJ, et al.
Zhongguo Zhong Yao Za Zhi = Zhongguo zhongYao ZaZhi = China Journal of Chinese Materia Medica, 28(1), 49-51 (2003)
Daidzin: a potent, selective inhibitor of human mitochondrial aldehyde dehydrogenase.
Keung MW and Vallee LB
Proceedings of the National Academy of Sciences of the USA, 90(4), 1247-1251 (1993)
Comparative study on reduction of bone loss and lipid metabolism abnormality in ovariectomized rats by soy isoflavones, daidzin, genistin, and glycitin.
Uesugi T, et al.
Biological & Pharmaceutical Bulletin, 24(4), 368-372 (2001)
Ting Zhang et al.
PloS one, 7(1), e30259-e30259 (2012-01-26)
New therapeutic tools and molecular targets are needed for treatment of Japanese encephalitis virus (JEV) infections. JEV requires an α-1 translational frameshift to synthesize the NS1' protein required for viral neuroinvasiveness. Several flavonoids have been shown to possess antiviral activity
Haiyang Zhang et al.
The journal of physical chemistry. B, 114(14), 4876-4883 (2010-03-20)
Puerarin and daidzin, two major isoflavonoids of Radix puerariae , are widely adopted in traditional Chinese medicine. Foundational aspects related to separating the two compounds are essential to develop a more economical purification process. Inclusion models of the two compounds

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