528240
Platelet Membrane Glycoproteins, IIbIIIa, Human Platelets
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About This Item
NACRES:
NA.25
UNSPSC Code:
12352202
Form:
liquid
Pricing and availability is not currently available.
form
liquid
Quality Segment
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
shipped in
wet ice
storage temp.
−70°C
General description
Native, platelet membrane glycoprotein IIbIIIaA from human platelets. A platelet integrin that binds to fibrinogen via the recognition sequence Arg-Gly-Asp-Ser. Acts as a receptor for such adhesive ligands as fibrinogen, fibronectin and von Willebrand factor during platelet stimulation. Glycoproteins IIb and IIIa constitute the fibrinogen receptor and are required for platelet aggregation. Glycoprotein IIb consists of two disulfide-linked subunits, GPIIbα and GPIIbβ, whereas GPIIIa has only one polypeptide chain.
Packaging
Please refer to vial label for lot-specific concentration.
Physical form
In 100 mM NaCl, 20 mM Tris-HCl, 1 mM CaCl2, 50% glycerol, ≤0.1% sodium azide, pH 7.4.
Preparation Note
Following initial thaw, aliquot and freeze (-70°C). Avoid freeze/thaw cycles.
Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Other Notes
Schwarz M., et al. 2004. J. Pharmacol. Exp. Therap.308, 1002.
Wippler, J., et al. 1994. J. Biol. Chem. 269, 8754.
Wippler, J., et al. 1994. J. Biol. Chem. 269, 8754.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
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This Item | |||
|---|---|---|---|
| form liquid | form lyophilized powder | form lyophilized powder | form lyophilized |
| shipped in wet ice | shipped in - | shipped in - | shipped in wet ice |
| storage condition OK to freeze | storage condition avoid repeated freeze/thaw cycles | storage condition avoid repeated freeze/thaw cycles | storage condition OK to freeze |
| storage temp. −70°C | storage temp. −20°C | storage temp. −20°C | storage temp. −70°C |
| Quality Level 100 | Quality Level 200 | Quality Level 100 | Quality Level 100 |
| manufacturer/tradename Calbiochem® | manufacturer/tradename - | manufacturer/tradename - | manufacturer/tradename Calbiochem® |
Storage Class
10 - Combustible liquids
wgk
WGK 1
signalword
Danger
hcodes
Hazard Classifications
ED ENV 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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