345831

Galectin-1, Human, Recombinant, E. coli

• Synonym(s): Lactose-binding lectin 1, Beta-galactoside-binding lectin L-14-I, S-Lac lectin 1, Galaptin, 14 kDa lectin, HPL, HBL, MAPK activating protein MP12
• UNSPSC Code: 12352202

Properties

• Assay: ≥98% (SDS-PAGE)
• Quality Level: 100
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• solubility: water: 0.1-1 mg/mL
• shipped in: wet ice
• storage temp.: −20°C

Description

General description

Recombinant human galectin-1 expressed in and purified from E. coli. Galectins are a family of evolutionarily conserved animal lectins with affinity for β-galactosides that have homologous carbohydrate recognition domains (CRDs). Galectin-1 can induce apoptosis of activated T cells and leukemic T cell lines. It also binds to CD45 and inhibits its protein phosphatase activity.

Recombinant, human galectin-1 expressed in E. coli. Galectins are a family of evolutionarily conserved animal lectins with affinity for β-galactosides that have homologous carbohydrate recognition domains (CRDs). Galectin-1 can induce apoptosis of activated T cells and leukemic T cell lines. It also binds to CD45 and inhibits its protein phosphatase activity.

Warning

Toxicity: Standard Handling (A)

Physical form

Lyophilized from sterile-filtered 20 mM Tris-HCl, pH 7.5.

Preparation Note

Further dilute into aqueous buffers as needed.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Diluted working solutions are stable for up to 1 week at 4°C or for up to 1 month at -20°C.

Other Notes

Rabinovich, A., et al. 2002. Trends Immunol.23, 313.
Rabinovich, A., et al. 2002. J. Leukoc. Biol.71, 741.
Hughes, R.C., et al. 2001. Biochimie.83, 667.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1