Recommended Products
biological source
goat
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
form
liquid
contains
≤0.1% sodium azide as preservative
species reactivity
human
manufacturer/tradename
Calbiochem®
availability
not available in Canada
storage condition
OK to freeze
avoid repeated freeze/thaw cycles
isotype
IgG
shipped in
ambient
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... CFH(3075)
General description
Anti-Factor H, goat polyclonal, recognizes Factor H in human. It is validated for Radial Immunodiffusion and Ouchterlony.
Goat polyclonal antibody supplied as undiluted serum. Recognizes Factor H.
Recognizes Factor H.
Immunogen
Human
purified, human factor H
Application
Radial Immunodiffusion (see comments)
Ouchterlony (≥ undiluted)
Ouchterlony (≥ undiluted)
Packaging
Please refer to vial label for lot-specific concentration.
Warning
Toxicity: Standard Handling (A)
Physical form
Undiluted serum.
Reconstitution
Following initial thaw, aliquot and freeze (-20°C).
Other Notes
This antibody has also been reported to work for radial immunodiffusion. Variables associated with assay conditions will dictate the proper working dilution.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Martin Ihnatko et al.
Frontiers in medicine, 8, 789972-789972 (2022-01-22)
COVID-19 vaccine-induced thrombotic thrombocytopenia (VITT) is a rare complication of adenoviral vector (ChAdOx1 nCoV-19) vaccine administration. It is presented as thrombocytopenia and thrombotic manifestations in various sites, especially in cerebral veins. Pulmonary emboli have been reported rarely. We present a
Anuj Pathak et al.
Nature communications, 9(1), 3398-3398 (2018-08-25)
Streptococcus pneumoniae evades C3-mediated opsonization and effector functions by expressing an immuno-protective polysaccharide capsule and Factor H (FH)-binding proteins. Here we use super-resolution microscopy, mutants and functional analysis to show how these two defense mechanisms are functionally and spatially coordinated
Jingyi Li et al.
Frontiers in immunology, 15, 1368322-1368322 (2024-04-01)
Activation of complement through the alternative pathway (AP) has a key role in the pathogenesis of IgA nephropathy (IgAN). We previously showed, by intraperitoneal injection of Lactobacillus casei cell wall extract (LCWE), C57BL/6 mice develop mild kidney damage in association
Federica Bianchi et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(11), 12099-12111 (2019-08-24)
The 4 component meningococcus B vaccine (4CMenB) vaccine is the first vaccine containing recombinant proteins licensed for the prevention of invasive meningococcal disease caused by meningococcal serogroup B strains. 4CMenB contains 3 main recombinant proteins, including the Neisseria meningitidis factor
Diana Pauly et al.
Cell reports, 29(9), 2835-2848 (2019-11-28)
Complement dysregulation is a feature of many retinal diseases, yet mechanistic understanding at the cellular level is limited. Given this knowledge gap about which retinal cells express complement, we performed single-cell RNA sequencing on ∼92,000 mouse retinal cells and validated
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