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20-265

Dithiothreitol, 1M

Synonym(s):

2,3-Butanediol, 1,4-dimercapto-, Cleland′s reagent, Sputolysin

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About This Item

UNSPSC Code:
41116012
NACRES:
NA.41
eCl@ss:
32160405
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solution

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manufacturer/tradename

Upstate®

shipped in

dry ice

Application

Dithiothreitol, 1M may be used as a reducing agent in sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) loading buffer.[1] It may also be used as a reagent in saliva sterilization.

Biochem/physiol Actions

Dithiothreitol (DTT), also known as Cleland′s reagent, is a reducing agent containing two thiol functional groups.[2] It serves as a protective regent for thiol groups in protein chemistry studies.[3] DTT is used in chemical peptide synthesis[4] for reducing disulfide bonds in various substrates such as glutathione, proteins, and other macromolecules.[3] It is also used as a mucolytic agent during sputum processing.[4]

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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D9760DTT-ROD5545
DTT crystalline powder, =97% (Ellman′s reagent), Mr 154.3

Roche

DTT-RO

DTT

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

200

form

solution

form

powder

form

crystalline powder

form

powder

shipped in

dry ice

shipped in

-

shipped in

-

shipped in

-

manufacturer/tradename

Upstate®

manufacturer/tradename

-

manufacturer/tradename

Roche

manufacturer/tradename

-


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Corrosion

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Danger

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Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials



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