Bufotenine is a hallucinogenic alkaloid found in mushrooms, plants, mammals and in toads belonging to the Bufo genus. This drug is structurally similar to psilocin, a psychedelic compound found in mushrooms. This Snap-N-Spike® Reference Solution is suitable for use in urine drug testing, clinical toxicology, or forensic analysis by LC-MS/MS or GC/MS.
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Several models of agonist binding to G protein-coupled 5-hydroxytryptamine [5-HT] (serotonin) receptors have highlighted the potential importance of highly conserved aromatic residues for ligand binding and agonist efficacy. In this study, we tested these models by constructing and characterizing a
There are many examples of a single receptor coupling directly to more than one cellular signal transduction pathway. Although traditional receptor theory allows for activation of multiple cellular effectors by agonists, it predicts that the relative degree of activation of
The Journal of pharmacology and experimental therapeutics, 280(2), 576-583 (1997-02-01)
In this study, the relationship between high-affinity agonist binding and second messenger production was examined at native and mutant 5-hydroxytryptamine2A receptors. At native 5-hydroxytryptamine2A receptors all agonists, with the exception of quipazine, discriminated between high- and low-affinity states of the
Journal of ethnopharmacology, 106(2), 198-202 (2006-02-04)
This paper is the first thorough analysis of takini, a hallucinogen used by the shamans of several peoples in Suriname, French Guiana, and the region east of the Para in Brazil. The drug is contained in the latex of the
Journal of forensic sciences, 41(6), 1068-1073 (1996-11-01)
The death of a 23-year-old man resulting from digoxin-like toxicity and heart failure was attributed to ingestion of a West Indian aphrodisiac known as "Love Stone." GC/MS analyses identified bufotenine, a controlled substance under both US and New York State
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