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M50400

Sigma-Aldrich

N-Methylhydroxylamine hydrochloride

98%

Synonym(s):

Methylhydroxylammonium chloride, N-Hydroxy-N-methanamine hydrochloride, N-Hydroxy-N-methylammonium chloride, N-Hydroxymethanamine hydrochloride, N-Hydroxymethylamine hydrochloride, N-Methylhydroxyamine hydrochloride, N-Methylhydroxylamine monohydrochloride, N-Methylhydroxylammonium chloride

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About This Item

Linear Formula:
CH3NHOH · HCl
CAS Number:
4229-44-1
Molecular Weight:
83.52
Beilstein:
3541409
EC Number:
224-181-2
MDL number:
MFCD00012597
UNSPSC Code:
12352100
PubChem Substance ID:
24896973
NACRES:
NA.22

Quality Level

200

Assay

98%

mp

86-88 °C (lit.)

SMILES string

Cl[H].CNO

InChI

1S/CH5NO.ClH/c1-2-3;/h2-3H,1H3;1H

InChI key

RGZRSLKIOCHTSI-UHFFFAOYSA-N

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Application

Used to construct hydroxamates, important functional groups for the complexation of iron.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Precautionary Statements

P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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S L Martins et al.
European journal of pharmacology, 284(3), 265-270 (1995-09-25)
The effects of the K+ channel blockers, apamin, tetraethylammonium and 4-aminopyridine, upon the relaxations of the isolated rat proximal duodenum induced by nitregic nerve activation, nitric oxide (NO), the NO donor 3-morpholinosydnonimine (SIN-1) and Br-cyclic GMP were determined. The effects
P S Brzović et al.
Biochemistry, 31(4), 1180-1190 (1992-02-04)
In an effort to understand the catalytic mechanism of the tryptophan synthase beta-subunit from Salmonella typhimurium, possible functional active site residues have been identified (on the basis of the 3-D crystal structure of the bienzyme complex) and targeted for analysis
Chunmei Geng et al.
ACS omega, 6(1), 358-366 (2021-01-19)
Doxorubicin (DOX) is widely used to treat solid tumors, but its use is limited by its severe cardiotoxicity, nephrotoxicity, hepatotoxicity, and neurotoxicity. Metabolomic studies on DOX-induced toxicity are mainly focused on alterations in the heart and kidney, but systematic research
Liang Zhao et al.
Chemistry, an Asian journal, 1(1-2), 203-209 (2007-04-19)
The three-component reaction of N-substituted hydroxylamines, aldehydes, and phenylacetylene catalyzed by CuCl/2,2'-bipyridine in the presence of NaOAc under neat conditions afforded the corresponding beta-lactams in good to excellent yields. Aromatic, heteroaromatic, and aliphatic aldehydes are tolerated in this reaction. The
A Gibson et al.
British journal of pharmacology, 96(3), 637-644 (1989-03-01)
1. The effects of N-methylhydroxylamine (NMH) and of M&B 22948 on relaxations of the mouse anococcygeus to non-adrenergic, non-cholinergic (NANC) field stimulation and to a number of smooth muscle relaxant drugs were investigated. 2. Relaxations to NANC field stimulation (10
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