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C101400

Sigma-Aldrich

1,2-Cyclohexanedione

97%

Synonym(s):

1,2-Dioxocyclohexane, Cyclohexan-1,2-dione

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About This Item

Linear Formula:
C6H8(=O)2
CAS Number:
765-87-7
Molecular Weight:
112.13
Beilstein:
507419
EC Number:
212-155-3
MDL number:
MFCD00001648
UNSPSC Code:
12352100
PubChem Substance ID:
24892299
NACRES:
NA.22

Assay

97%

form

solid

bp

193-195 °C (lit.)

mp

34-38 °C (lit.)

storage temp.

2-8°C

SMILES string

O=C1CCCCC1=O

InChI

1S/C6H8O2/c7-5-3-1-2-4-6(5)8/h1-4H2

InChI key

OILAIQUEIWYQPH-UHFFFAOYSA-N

Gene Information

human ... ACHE(43) , BCHE(590) , CES1(1066)

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Application

Specific reagent for arginine residues.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

No data available

Flash Point(C)

No data available

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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D Scott Wilbur et al.
Bioconjugate chemistry, 13(3), 611-620 (2002-05-16)
Recombinant streptavidin (rSAv) is of interest as a carrier of alpha-emitting radionuclides in pretargeting protocols for cancer therapy. Due to the inherently high kidney localization of rSAv, modification of this protein is required before it can be useful in pretargeting.
Andres De la Rossa et al.
Nature neuroscience, 16(2), 193-200 (2013-01-08)
The molecular mechanisms that control how progenitors generate distinct subtypes of neurons, and how undifferentiated neurons acquire their specific identity during corticogenesis, are increasingly understood. However, whether postmitotic neurons can change their identity at late stages of differentiation remains unknown.
C Cervenanský et al.
European journal of biochemistry, 229(1), 270-275 (1995-04-01)
The West African green mamba, Dendroaspis angusticeps, has two toxins, fasciculins, that are non-competitive inhibitors of acetylcholinesterase. Arginine residues of fasciculin 2 were modified with 1,2-cyclohexanedione. Two of these residues, Arg24 and Arg37, reacted very slowly or not at all.
S Adak et al.
The Biochemical journal, 314 ( Pt 3), 985-991 (1996-03-15)
The plausible role of arginine and tyrosine residues at the active side of horseradish peroxidase (HRP) in aromatic donor (guaiacol) oxidation was probed by chemical modification followed by characterization of the modified enzyme. The arginine-specific reagents phenylglyoxal (PGO), 2,3-butanedione and
Bellamkonda Ramakrishna et al.
International journal of biological macromolecules, 115, 1225-1232 (2018-05-05)
The recombinant C-terminal domain of chitinase C of Chitinophaga pinensis (CpChiC-GH18C) exhibits the highest activity at pH 6.0 and 35 °C, with a Km of 76.13 (mg-1 ml), a kcat of 10.16 (s-1), and a kcat/Km of 0.133 (mg-1 ml s-1) on colloidal chitin. Analysis
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