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A45807

Sigma-Aldrich

2-Amino-5-chlorobenzoxazole

97%

Synonym(s):

Zoxazolamine

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About This Item

Empirical Formula (Hill Notation):
C7H5ClN2O
CAS Number:
61-80-3
Molecular Weight:
168.58
EC Number:
200-519-4
MDL number:
MFCD00005770
UNSPSC Code:
12352100
PubChem Substance ID:
24890884
NACRES:
NA.22

Assay

97%

form

powder

mp

181-184 °C (lit.)

SMILES string

Nc1nc2cc(Cl)ccc2o1

InChI

1S/C7H5ClN2O/c8-4-1-2-6-5(3-4)10-7(9)11-6/h1-3H,(H2,9,10)

InChI key

YGCODSQDUUUKIV-UHFFFAOYSA-N

Related Categories

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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D J Hadjipavlou-Litina et al.
Research communications in molecular pathology and pharmacology, 96(3), 307-318 (1997-06-01)
Some modified novel thiazol-5yl-aminoketones were evaluated for their anti-inflammatory, analgesic and antiproteolytic activities. Their inhibitory activity on 12-lipoxygenase (12-LO) and beta-glucuronidase in vitro was estimated. Their interaction with the stable free radical 1,1-diphenyl-2-picrylhydrazyl (DPPH) and their RM values were also
K K Anand et al.
Pharmacological research, 36(4), 315-321 (1998-01-13)
Compound I isolated from fraction TB5 of Terminalia belerica and finally identified as 3,4,5-trihydroxy benzoic acid (gallic acid) was evaluated for its hepatoprotective activity against carbon tetrachloride (CCl4)-induced physiological and biochemical alterations in the liver. The main parameters studied were
Cong Zhang et al.
Nature medicine, 14(9), 959-965 (2008-08-12)
Chaperone-mediated autophagy (CMA), a selective mechanism for degradation of cytosolic proteins in lysosomes, contributes to the removal of altered proteins as part of the cellular quality-control systems. We have previously found that CMA activity declines in aged organisms and have
Juan P Hernandez et al.
Toxicological sciences : an official journal of the Society of Toxicology, 98(2), 416-426 (2007-05-08)
Nonylphenol (NP) and its parent compounds, the nonylphenol ethoxylates are some of the most prevalent chemicals found in U.S. waterways. NP is also resistant to biodegradation and is a known environmental estrogen, which makes NP a chemical of concern. Our
I Andreadou et al.
European journal of drug metabolism and pharmacokinetics, 28(1), 7-10 (2003-09-25)
The influence of four ethanolamine derivatives with anti-inflammatory and antioxidant activity on the in vitro aminopyrine N-demethylation was studied. It was found that these compounds inhibit the N-demethylation of aminopyrine. 1-Cyclohexyl-5-(2-hydroxy-ethylamino)-pentan-2-one (compound 4), possessing the highest inhibitory activity and found
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