Skip to Content
Merck
All Photos(1)

Documents

369055

Sigma-Aldrich

2-Bromo-4-fluoroaniline

97%

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
BrC6H3(F)NH2
CAS Number:
1003-98-1
Molecular Weight:
190.01
MDL number:
MFCD00042462
UNSPSC Code:
12352100
PubChem Substance ID:
24862951

Assay

97%

form

solid

refractive index

n20/D 1.583 (lit.)

bp

221 °C (lit.)

density

1.67 g/mL at 25 °C (lit.)

SMILES string

Nc1ccc(F)cc1Br

InChI

1S/C6H5BrFN/c7-5-3-4(8)1-2-6(5)9/h1-3H,9H2

InChI key

YLMFXCIATJJKQL-UHFFFAOYSA-N

General description

2-Bromo-4-fluoroaniline is an aryl fluorinated building block.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

219.2 °F - closed cup

Flash Point(C)

104 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

An efficient synthesis of enantiomerically pure aromatic-fused N-containing heterocycles from common chiral aziridines.
Chan Kim J, et al.
Tetrahedron, 66(40), 8108-8114 (2010)
Synthesis of fluorescent tetracyclic lactams by a ?one pot? three steps palladium-catalyzed borylation, Suzuki coupling (BSC) and lactamization: DNA and polynucleotides binding studies.
Queiroz M-JRP, et al.
Journal of Photochemistry and Photobiology A: Chemistry, 190(1), 45-52 (2007)
Fatma K Abdel-Wadood et al.
Archiv der Pharmazie, 347(2), 142-152 (2014-01-01)
2-Bromo-4-fluoroaniline (1) was condensed with ethyl 2-cyano-3-ethoxyacrylate (2) in ethanol to afford 3, which upon refluxing in paraffin oil at 250°C gave 8-bromo-3-cyano-6-fluoroquinoline-4(1H)-one (4). Then, compound 4 was taken as a versatile building block that allows the synthesis of thieno[3,2-c]quinoline

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service