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Merck

SAT1

spermidine/spermine N1-acetyltransferase 1

Synonyms:
DC21, KFSD, KFSDX, SAT, SSAT, SSAT-1
Species:
UniProtKB ID:
Gene ID:
  • Human(6303) Summary: The protein encoded by this gene belongs to the acetyltransferase family, and is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. It catalyzes the acetylation of spermidine and spermine, and is involved in the regulation of the intracellular concentration of polyamines and their transport out of cells. Defects in this gene are associated with keratosis follicularis spinulosa decalvans (KFSD). Alternatively spliced transcripts have been found for this gene.[provided by RefSeq, Sep 2009]
  • Mouse(20229) spermidine/spermine N1-acetyl transferase 1
  • Rat(302642) spermidine/spermine N1-acetyl transferase 1
  • sheep(101113463) spermidine/spermine N1-acetyltransferase 1
  • cow(508861) spermidine/spermine N1-acetyltransferase 1
  • dog(480865) spermidine/spermine N1-acetyltransferase 1
  • domestic cat(101093752) spermidine/spermine N1-acetyltransferase 1
  • domestic guinea pig(100715782) spermidine/spermine N1-acetyltransferase 1
  • chicken(374006) spermidine/spermine N1-acetyltransferase 1
  • naked mole-rat(101726536) spermidine/spermine N1-acetyltransferase 1

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SAT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SAT1,
Species
human