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Merck

KLK3

kallikrein-related peptidase 3

Synonyms:
APS, KLK2A1, PSA, hK3
Species:
Human KLK3 (354)
UniProtKB ID:
P07288, C9JXH3, G3V0H4, G3XAE3, Q15096, Q16272, Q86TG8, Q8IXI4
Gene ID:
  • Human(354) Summary: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

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ELISA

Product Number
Description
Species
RAB0729
Human KLK3 / Prostate-specific Antigen ELISA Kit, ,
Species
human
RAB0331
Human PSA-total ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
WH0000354M2
Monoclonal Anti-KLK3 antibody produced in mouse, clone 1B1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
SAB1405474
Anti-KLK3 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
HPA000764
Anti-KLK3 antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
SAB1410703
Anti-KLK3 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
proximity ligation assay
western blot
SAB4702007
Monoclonal Anti-PSA Biotin produced in mouse, ,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
SRP6058
Kallikrein-3 human, recombinant, expressed in human cells, ≥95% (SDS-PAGE),
Species
human
P3235
Prostate Specific Antigen from human semen, buffered aqueous solution,
Species
human
P3338
Prostate Specific Antigen from human semen, buffered aqueous solution,
Species
human
P3360
Prostate Specific Antigen–α1-Antichymotrypsin Complex human, ≥99% (SDS-PAGE), buffered aqueous solution,
Species
human

esiRNA

Product Number
Description
Species
EHU156951
MISSION® esiRNA, targeting human KLK3,
Species
human