I3265
Interferon-γ human
recombinant, expressed in E. coli, ≥98% (SDS-PAGE), lyophilized powder, suitable for cell culture
Synonym(s):
IFN-γ
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Recommended Products
biological source
human
Quality Level
recombinant
expressed in E. coli
Assay
≥98% (SDS-PAGE)
form
lyophilized powder
mol wt
~17 kDa
packaging
pkg of 0.1 mg
technique(s)
cell culture | mammalian: suitable
impurities
≤1 EU/μg endotoxin
color
white
solubility
water: soluble 1.000 mL, clear, colorless
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... IFNG(3458)
Looking for similar products? Visit Product Comparison Guide
Application
Interferon-γ human has been used:
- to study the effect of interferon-γ on cultured trophoblasts in absence and presence of fibronectin
- to analyse factors which participate in the production of antibody microarrays on glass support
- for ELISA (enzyme-linked immunosorbent assay) method to understand the effect of interferon-γ in human gingival fibroblasts in presence of bacterial challenge
Biochem/physiol Actions
IFNG (interferon-γ) is a type-2 interferon which is produced by Th (T helper cells)-1 lymphocytes, CD8 cytotoxic lymphocytes, natural killer (NK) cells, and natural killer T (NKT) cells. It plays an important role in innate and adaptive immune responses, and helps in defense against bacterial infections, dimorphic yeast and some viral infections. High expression of IFNG is common in many autoimmune diseases, such as systemic lupus erythematosis, Sjögren syndrome, inflammatory bowel disease and multiple sclerosis.
Physical form
Lyophilized from phosphate buffered saline.
Analysis Note
The biological activity is measured by a viral resistance assay.
related product
Product No.
Description
Pricing
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
K Pfizenmaier et al.
Cancer research, 45(8), 3503-3509 (1985-08-01)
The effect of recombinant gamma-interferon (IFN-gamma) on established human colon carcinoma cell lines as well as fresh tumor cells from colon carcinoma patients has been investigated with respect to growth inhibition, enhancement of HLA expression, and modulation of immunogenicity. A
R Pijnenborg et al.
Molecular human reproduction, 6(7), 635-641 (2000-06-29)
Tumour necrosis factor (TNF)-alpha and interferon (IFN)-gamma, produced by maternal inflammatory cells, may compromise trophoblast survival at the trophoblast-maternal interface and notably in the placental bed which is invaded by trophoblast. Extracellular matrix components, e.g. fibronectin, may enhance trophoblast survival.
Marielle Kaplan et al.
Inflammation, 41(4), 1477-1487 (2018-04-25)
Arterial macrophages comprise a heterogeneous population: pro-inflammatory (M1) and anti-inflammatory (M2). Since C-reactive protein (CRP) is produced by macrophages in atherosclerotic lesions, understanding of CRP regulation in macrophages could be crucial to decipher inflammatory patterns in atherogenesis. We aimed to
Wlad Kusnezow et al.
Proteomics, 3(3), 254-264 (2003-03-11)
Antibody microarrays could have an enormous impact on the functional analysis of cellular activity and regulation, especially at the level of protein expression and protein-protein interaction, and might become an invaluable tool in disease diagnostics. The array surface is bound
M J Lappin et al.
Archives of oral biology, 61, 36-43 (2015-10-30)
To investigate the potential effects of IFN-03A5 on the responsiveness of human gingival fibroblasts to bacterial challenge. mRNA and protein expression of CD14, TLR2 and TLR4 in human gingival fibroblasts was detected by quantitative polymerase chain reaction (Q-PCR) and flow
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service