06627
2-Aminoacridone
BioReagent, suitable for fluorescence, ≥98.0% (HPLC)
Synonym(s):
2-Amino-9(10H)-acridinone, 2-amino-10H-acridin-9-one, AMAC
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About This Item
Empirical Formula (Hill Notation):
C13H10N2O
CAS Number:
Molecular Weight:
210.23
Beilstein:
172520
MDL number:
UNSPSC Code:
12352108
PubChem Substance ID:
NACRES:
NA.32
Recommended Products
product line
BioReagent
Assay
≥98.0% (HPLC)
solubility
DMF: soluble
DMSO: soluble
fluorescence
λex 420 nm; λem 542 nm in 0.1 M Tris pH 8.0
suitability
suitable for fluorescence
SMILES string
Nc1ccc2Nc3ccccc3C(=O)c2c1
InChI
1S/C13H10N2O/c14-8-5-6-12-10(7-8)13(16)9-3-1-2-4-11(9)15-12/h1-7H,14H2,(H,15,16)
InChI key
PIGCSKVALLVWKU-UHFFFAOYSA-N
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Application
2-Aminoacridone is a highly fluorescent aromatic, which contains a primary amine group that reacts with an aldehyde group at the reducing end of a carbohydrate and is reduced to a stable amine derivative by sodium borohydride (NaBH4). Picomolar levels of glycan compounds can be detected using this fluorophore. The resulting derivatzed compounds can be separated by reverse-phase HPLC and detected by positive-ion electrospray MS . An intense fluorescent, hydrophobic probe that is stable over a wide pH range is useful in the derivatization of glycans to allow for the analysis of complex oligosaccharides using micellar electrokinetic capillary chromatography and reverse- and normal-phase chromatography coupled with mass spectroscopy to determine relative concentrations and structural identity of individual oligosaccharides . The λ excitation and λ emission are 425 nm and 532 nm, respectively.
Fluorescent label for glycans and saccharides.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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