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ECM554

Sigma-Aldrich

QCM ECMatrix Cell Invasion Assay, 24-well (8 µm), fluorimetric

The Cell Invasion Assay Kit kuses a 24 well plate with 8 um pores, which is ideal for evaluation of invasive tumor cells.

Synonym(s):

Cell invasion assessment kit

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About This Item

UNSPSC Code:
12352207
eCl@ss:
32161000
NACRES:
NA.84

Quality Level

species reactivity

vertebrates

manufacturer/tradename

Chemicon®
QCM

technique(s)

cell based assay: suitable

detection method

fluorometric

shipped in

wet ice

Application

Research Category
Cell Structure
The CHEMICON® Cell Invasion Assay Kit is ideal for evaluation of invasive tumor cells. Each CHEMICON Cell Invasion Assay Kit contains sufficient reagents for the evaluation of 24 samples. The quantitative nature of this assay is especially useful for screening of pharmacological agents.

The CHEMICON Cell Invasion Assay Kit is intended for research use only; not for diagnostic or therapeutic applications.
The Cell Invasion Assay Kit kuses a 24 well plate with 8 um pores, which is ideal for evaluation of invasive tumor cells.

Packaging

24 assays

Components

Sterile 24-well Cell Invasion Plate Assembly: (Part No. 70019) Two 24-well plates with 12 ECMatrixTM-coated inserts per plate (24 coated inserts total/kit for 24 assays).

Cell Detachment Solution: (Part Number 90131) One bottle - 16 mL.

4X Cell Lysis Buffer: (Part Number 90130) One bottle - 16 mL.

CyQuant GR Dye 1: (Part Number 90132) One vial - 75 mL

Forceps: (Part Number 10203) One each.

Storage and Stability

Store kit materials at 2-8°C for up to their expiration date. Do not freeze.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pictograms

CorrosionEnvironment

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 2


Certificates of Analysis (COA)

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Bei Wang et al.
Journal of hepatology, 50(3), 528-537 (2009-01-22)
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death worldwide with poor prognosis associated with tumor invasion and metastasis. The tumor suppressor p53 plays critical roles in tumor development, but there is increasing evidence for its involvement
Roberta M Moretti et al.
International journal of oncology, 33(2), 405-413 (2008-07-19)
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Xujun He et al.
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Increased expression of HOXB7 has been reported to correlate with the progression in many cancers. However, the specific mechanism by which it promotes the evolution of gastric cancer (GC) is poorly understood.In this study, we sought to investigate the role
Sarah M Peterson et al.
BMC cancer, 10, 427-427 (2010-08-17)
Extracellular human sulfatases modulate growth factor signaling by alteration of the heparin/heparan sulfate proteoglycan (HSPG) 6-O-sulfation state. HSPGs bind to numerous growth factor ligands including fibroblast growth factors (FGF), epidermal growth factors (EGF), and vascular endothelial growth factors (VEGF), and
Ping Feng et al.
The international journal of biochemistry & cell biology, 40(1), 98-109 (2007-08-19)
Cyr61/CCN1 is a secreted extracellular matrix associated protein involved in diverse biological functions and plays multiple roles in tumorigenesis. Cyr61 was down-regulated in HCC tumor tissues as observed in our previous cDNA microarray study, but its potential role in hepatocarcinogenesis

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