217503
Cardiotoxin
from Naja pallida, ≥95% (HPLC), lyophilized solid, cytolytic toxin, Calbiochem®
Synonym(s):
Cardiotoxin, Naja pallida
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Recommended Products
product name
Cardiotoxin, Naja pallida,
Assay
≥95% (HPLC)
Quality Level
form
lyophilized solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
solubility
water: 1 mg/mL
shipped in
ambient
storage temp.
2-8°C
General description
Cardiotoxins, which are highly basic peptides, interact with negatively charged lipids on membranes. While the presence of Lysine residues is crucial for their activity, cardiotoxins demonstrate varying effects on different cells, indicating selective binding to certain cell types.
Application
Cardiotoxin, Naja pallida has been used:
- to inject into the TA of the 4-month-old dystrophic mice to address whether ILA treatment could modulate muscle regeneration
- to induce a skeletal muscle injury into the right TA muscle
- to induce muscle regeneration
Warning
Toxicity: Harmful (C)
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Jang, J.Y., et al. 1997. Biochemistry 36, 4635.
Huang, J.L., and Trumble, W.R. 1991. Toxicon29, 31.
Raynor, R.L., et al. 1991. J. Biol. Chem.266, 2753.
Grognet, J.M., et al. 1986. Mol. Immunol.23, 132.
Huang, J.L., and Trumble, W.R. 1991. Toxicon29, 31.
Raynor, R.L., et al. 1991. J. Biol. Chem.266, 2753.
Grognet, J.M., et al. 1986. Mol. Immunol.23, 132.
Legal Information
Not available for sale outside of the United States.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Deficiency of skeletal muscle Agrin contributes to the pathogenesis of age-related sarcopenia in mice
Chen J, et al.
Cell Death & Disease, 15(3), 201-201 (2024)
Snake peptides
Harvey, Alan L
Handbook of Biologically Active Peptides (2013)
DOCK3 regulates normal skeletal muscle regeneration and glucose metabolism
Samani A, et al.
bioRxiv : the preprint server for biology (2023)
Valeria Yartseva et al.
Cell reports, 30(5), 1491-1503 (2020-02-06)
How satellite cells and their progenitors balance differentiation and self-renewal to achieve sustainable tissue regeneration is not well understood. A major roadblock to understanding satellite cell fate decisions has been the difficulty of studying this process in vivo. By visualizing expression
Evaluation of pro-regenerative and anti-inflammatory effects of isolecanoric acid in the muscle: Potential treatment of Duchenne Muscular Dystrophy
Matias-Valiente L, et al.
Biomedicine and Pharmacotherapy, 170, 116056-116056 (2024)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service