911259
Poly(ethylene glycol) linear dendrimer
carboxyl terminated, PEG Mn 10k, generation 3
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About This Item
Empirical Formula (Hill Notation):
C588H1086O318
Molecular Weight:
13244.72
UNSPSC Code:
12352120
NACRES:
NA.23
Recommended Products
form
solid
mol wt
PEG Mn 10k
PEG average Mn 10,000
generation 3
no. Surface Groups
16
color
white to off-white
functional group
carboxylic acid
storage temp.
−20°C
General description
- Polymer architecture: PEG-core dendrimer
- End Group Functionality: Carboxylic acid
- Bis-MPA : 2,2-Bis(hydroxymethyl)propionic acid
Application
Bis-MPA dendritic molecules are based on 2,2-bismethylolpropionicacid (bis-MPA) building blocks. The hydrolyzable linker allows for degradation into byproducts that can be reabsorbed by the body or into excretable non-toxic small molecules. This dendritic polymer is biocompatible, biodegradable, and suitable for biomedical applications. PEG-core dendrimers feature excellent solubility in water and a high degree of functionality per PEG chain, enabling use for advanced drug delivery systems or for drug targeting. The carboxylic acid-functionalized corona can be readily used for bioconjugation reactions.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications
Garcia-Gallego S, et al
Progress in Polymer Science, 48, 85-110 (2015)
Anna Carlmark et al.
Chemical Society reviews, 42(13), 5858-5879 (2013-05-01)
Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been
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