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910813

Sigma-Aldrich

mPEG24-NHS

Synonym(s):

Methoxypolyethylene glycol acetic acid N-succinimidyl ester, mPEG NHS

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About This Item

Empirical Formula (Hill Notation):
C56H107NO29
CAS Number:
174569-25-6
Molecular Weight:
1258.44
MDL number:
MFCD28385538
UNSPSC Code:
43211915
NACRES:
NA.23

Assay

95% (HPLC)

form

solid

mol wt

average Mn 1,250 (by NMR)

reaction suitability

reagent type: chemical modification reagent
reactivity: amine reactive

color

white to off-white

Ω-end

NHS ester

α-end

methoxy

polymer architecture

shape: linear
functionality: monofunctional

storage temp.

−20°C

Related Categories

Application

Polyethylene glycols (PEGs) are FDA approved hydrophilic polymers. They are non-toxic, non-immunogenic and non-antigenic, and are widely used in a variety of biomedical applications such as bioconjugation, drug delivery, surface functionalization, and tissue engineering. PEG-NHS is an amine reactive PEG that can react to amino groups of lysine(s) on proteins or other biologics; reaction occurs at room temperature in <1hr at pH 7-8. Stable linker between PEG and NHS ester.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

>230.0 °F

Flash Point(C)

> 110 °C

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