163821

3-Methoxy-2-nitrobenzaldehyde

≥97%

• Linear Formula: CH₃OC₆H₃(NO₂)CHO
• CAS Number: 53055-05-3
• Molecular Weight: 181.15
• Beilstein: 1959385
• EC Number: 258-332-9
• MDL number: MFCD00007135
• UNSPSC Code: 12352100
• PubChem Substance ID: 24850038
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: ≥97%
• form: solid
• mp: 97-101 °C (lit.)
• functional group: aldehyde; nitro
• SMILES string: [H]C(=O)c1cccc(OC)c1[N+]([O-])=O
• InChI: 1S/C8H7NO4/c1-13-7-4-2-3-6(5-10)8(7)9(11)12/h2-5H,1H3
• InChI key: GDTUACILWWLIJF-UHFFFAOYSA-N

Description

General description

3-Methoxy-2-nitrobenzaldehyde undergoes 1,4-diazabicyclo[2.2.2]octane-catalyzed reaction with methyl vinyl ketone (MVK) to afford normal Baylis-Hillman adduct, the MVK dimer and a pair of diastereomeric bis-(MVK)Baylis-Hillman adducts.

Application

3-Methoxy-2-nitrobenzaldehyde was used in the synthesis of 8-hydroxyquinazoline, methy-3-methoxyanthranilate and 3-methoxy-2-nitrobenzylidenebisformamide.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves