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H5882

Sigma-Aldrich

Hexadecyltrimethylammonium bromide

≥98%

Synonym(s):

CTAB, Cetrimonium bromide, Cetyltrimethylammonium bromide, Palmityltrimethylammonium bromide

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About This Item

Linear Formula:
CH3(CH2)15N(Br)(CH3)3
CAS Number:
57-09-0
Molecular Weight:
364.45
Beilstein:
3598189
EC Number:
200-311-3
MDL number:
MFCD00011772
UNSPSC Code:
12161900
PubChem Substance ID:
24895714
NACRES:
NA.21

description

cationic

Assay

≥98%

form

(solids)

mol wt

micellar avg mol wt 62,000

aggregation number

170

technique(s)

DNA extraction: suitable
RNA extraction: suitable

pH

5.0-7 (25 °C, 36.4 g/L)

CMC

0.92 mM (20-25°C)

mp

248-251 °C (lit.)

solubility

H2O: 100 mg/mL

HLB

10

SMILES string

[Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C

InChI

1S/C19H42N.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(2,3)4;/h5-19H2,1-4H3;1H/q+1;/p-1

InChI key

LZZYPRNAOMGNLH-UHFFFAOYSA-M

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General description

Hexadecyltrimethylammonium bromide, a bactericidal, is a cationic detergent. Its activity can be neutralized by soaps and anionic detergents. Cetyltrimethylammonium bromide (CTAB) is effective against Gram-positive and Gram-negative bacteria at alkaline pH.

Application

Hexadecyltrimethylammonium bromide has been used:
  • as a component in sodium phosphate buffer to homogenize tissues for determining myeloperoxidase activity
  • in the synthesis of gold nanorods with surface plasmon resonance for a comparative study
  • in the synthesis of gold nanorods to study the influence of good hexadecyltrimethylammonium bromide (CTAB) and CTAB with iodide impurities on the synthesis

Biochem/physiol Actions

Hexadecyltrimethylammonium bromide or cetyltrimethylammonium bromide (CTAB) can be used to isolate plant high molecular weight DNA (by a rapid method) as well as plant DNA for use in polymerase chain reaction (PCR) analysis. It plays a key role in precipitating nucleic acids. CTAB can be used as titrant for potentiometric titration of perchlorate. It can also be used as a phase-transfer catalyst in the reduction of arenes and heterocyclic compounds. It is suitable for determining protein molecular weights in electrophoretic systems. CTAB can also be used to determine critical micelle concentration of detergents.

Features and Benefits

  • Provides enhancement of concanavalin A mediated agglutination

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2 - STOT RE 2 Oral - STOT SE 3

Target Organs

Gastrointestinal tract, Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

471.2 °F - closed cup

Flash Point(C)

244 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Rodrigo Jiménez-Saiz et al.
Frontiers in immunology, 11, 155-155 (2020-03-03)
Eosinophils have emerged as multifaceted cells that contribute to tissue homeostasis. However, the impact of the microbiota on their frequency and function at mucosal sites remains unclear. Here, we investigated the role of the microbiota in the regulation of enteric
Raja Gopal Rayavarapu et al.
Langmuir : the ACS journal of surfaces and colloids, 26(7), 5050-5055 (2010-03-09)
Recent reports [Smith and Korgel Langmuir 2008, 24, 644-649 and Smith et al. Langmuir 2009, 25, 9518-9524] have implicated certain hexadecyltrimethylammonium bromide (CTAB) products with iodide impurities, in the failure of a seed-mediated, silver and surfactant-assisted growth protocol, to produce
Israa Haidar et al.
Physical chemistry chemical physics : PCCP, 18(47), 32272-32280 (2016-11-17)
The controlled assembly of anisotropic plasmonic nanoparticles (NPs) into highly SERS-active substrates remains particularly challenging for the production of long-term stable NP assemblies in suspension. In this work, we report a simple and efficient strategy to assemble gold nanorods (AuNRs)
K Maki et al.
Biochemical and biophysical research communications, 175(3), 768-774 (1991-03-29)
We investigated conditions for selective solubilization of the intermediate filament (IF) of BHK-21 cells, and found that a cationic detergent, cetyltrimethylammonium bromide (CTAB), was effective for rapid dissociation of IF into the monomeric form. More selective dissociation was performed with
Lonneke Onrust et al.
Veterinary research, 51(1), 56-56 (2020-04-21)
Butyrate has been used extensively as a feed additive to improve gut health and to decrease Salmonella colonization in poultry. Salmonella mainly colonizes the ceca so butyrate concentrations should be increased in this gut segment. Discrepancies on the effects of
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