The purity of this product is not determined.
A7003
Alginic acid from brown algae
powder
Synonym(s):
Alginic acid from Macrocystis pyrifera (kelp), Mixed polymer of mannuronic and guluronic acid
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All Photos(5)
About This Item
Linear Formula:
(C6H8O6)n
CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12171500
NACRES:
NA.47
Pricing and availability is not currently available.
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form
powder
Quality Level
technique(s)
titration: suitable
color
white to light yellow
pH range
1.5-3.5
mp
300 °C
solubility
H2O: insoluble, but swells
aqueous base: soluble
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
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General description
Alginic acid is a high molecular weight linear polymer isolated from seaweed. It is a linear β-1→4-linked polymer of n-mannuronic and L-guluronic acid. It is an acid polysaccharide present in the extracellular matrix of brown algae.[1] It is reported to inhibit the reverse transcriptase activity of HIV.[1] Structural investigation of alginic acid, a marine algal polysaccharide poly-α-L-guluronic acid, has been reported.[2] Anti-inflammatory effect of alginic acid, isolated from the brown algae Sargassum wightii, in type II collagen induced arthritic rats has been reported.[3] Pyrolysis of alginic acid using py-GC/MS over a wide temperature range (200-800°C) and thermogravimetric analysis (TGA) has been reported.[4] It was reported to cause the biocorrosion of thin films of copper on germanium internal reflection elements (IREs).[5]
Application
Other Notes
A straight-chain, hydrophilic, colloidal, polyuronic acid composed primarily of anhydro-β-D-mannuronic acid residues with 1→4 linkage.
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Structural components of alginic acid. II. The crystalline structure of poly-alpha-L-guluronic acid. Results of x-ray diffraction and polarized infrared studies.
E D Atkins et al.
Biopolymers, 12(8), 1879-1887 (1973-01-01)
C H Sarithakumari et al.
International immunopharmacology, 17(4), 1108-1115 (2014-01-22)
The present study evaluated the anti-inflammatory potential of alginic acid isolated from the brown algae Sargassum wightii in type II collagen induced arthritic rats, a well established arthritic model that resembles more closely to human rheumatoid arthritis in its clinical
Ramón Rial et al.
Nanomaterials (Basel, Switzerland), 10(7) (2020-07-09)
Hydrogels exhibit excellent properties that enable them as nanostructured scaffolds for soft tissue engineering. However, single-component hydrogels have significant limitations due to the low versatility of the single component. To achieve this goal, we have designed and characterized different multi-component
In situ, real-time FT-IR/CIR/ATR study of the biocorrosion of copper by gum arabic, alginic acid, bacterial culture supernatant and Pseudomonas atlantica exopolymer.
Jolley JG, et al.
Applied Spectroscopy, 43(6), 1062-1067 (1989)
K C S Queiroz et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 62(5), 303-307 (2008-05-06)
Brown algae have two kinds of acid polysaccharides present in the extracellular matrix: sulfated fucan and alginic acid. We have previously isolated and characterized fucans from several species of brown seaweed. The characterized fucans from Dictyotaceae are heterofucans containing mainly
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What is the purity of the product?
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What is the M:G ratio for A7003 alginic acid?
1 answer-
The mannuronic and guluronic content of the alginic acid in product A7003 is not a measured. The information stated on the product datasheet - 61% mannuronic acid and 39% guluronic acid - is on the basis of what is reported in the literature. Please see the link below to review the Product Information Sheet:
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/376/103/a7003pis.pdfHelpful?
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