D182001
3,5-Dimethylpyrazole
99%
Synonym(s):
3,5-Dimethyl-1H-pyrazole
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About This Item
Empirical Formula (Hill Notation):
C5H8N2
CAS Number:
Molecular Weight:
96.13
Beilstein:
106325
EC Number:
MDL number:
UNSPSC Code:
12352100
eCl@ss:
39160503
PubChem Substance ID:
NACRES:
NA.22
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Assay
99%
form
powder
bp
218 °C (lit.)
mp
105-108 °C (lit.)
SMILES string
Cc1cc(C)[nH]n1
InChI
1S/C5H8N2/c1-4-3-5(2)7-6-4/h3H,1-2H3,(H,6,7)
InChI key
SDXAWLJRERMRKF-UHFFFAOYSA-N
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Application
Common reagent for the preparation of pyrazolato ligated complexes. Also used to prepare N-1-substituted derivatives having antibacterial activity.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - STOT RE 2
Target Organs
Liver
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Journal of Organometallic Chemistry, 443, 221-221 (1993)
J. Chem. Soc., Dalton Trans., 3625-3625 (1993)
J. Chem. Soc. Pak., 14, 125-125 (1992)
E Bergamini et al.
The American journal of physiology, 266(1 Pt 1), G118-G122 (1994-01-01)
Regulation of liver macroautophagy and protein degradation by hormones and direct regulatory amino acids were studied in male 2-mo-old Sprague-Dawley albino rats with the use of the antilipolytic agent 3,5'-dimethylpyrazole (DMP; 12 mg/kg body wt ip) as a stimulatory agent.
Gabriella Cavallini et al.
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Autophagy is a major intracellular degradation/recycling system ubiquitous in eukaryotic cells. It contributes to the turnover of cellular components by delivering portions of the cytoplasm and organelles to lysosomes, where they are digested. Starvation-induced autophagy is required for maintaining an
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