532711

2-Fluorobenzenesulfonyl chloride

97%

• Linear Formula: FC₆H₄SO₂Cl
• CAS Number: 2905-21-7
• Molecular Weight: 194.61
• MDL number: MFCD00042285
• UNSPSC Code: 12352100
• PubChem Substance ID: 24877907
• NACRES: NA.22

Properties

• Assay: 97%
• refractive index: n20/D 1.537 (lit.)
• bp: 246-247 °C (lit.)
• mp: 27-30 °C (lit.)
• density: 1.47 g/mL at 25 °C (lit.)
• functional group: fluoro
• SMILES string: Fc1ccccc1S(Cl)(=O)=O
• InChI: 1S/C6H4ClFO2S/c7-11(9,10)6-4-2-1-3-5(6)8/h1-4H
• InChI key: ZSZKAQCISWFDCQ-UHFFFAOYSA-N

Description

General description

2-Fluorobenzenesulfonyl chloride, also known as o-fluorobenzenesulfonyl chloride, is a flurinated arylsulfonyl chloride. It can be prepared from o-benzenedisulfonyl fluoride.

Application

2-Fluorobenzenesulfonyl chloride may be used in the preparation of the following furan derivatives:

• 2-(2-fluorophenyl)benzofuran
• 2-butyl-5-(2-fluorophenyl)furan
• 2-(2-fluorophenyl)-3,6-dimethyl-4,5,6,7-tetrahydrobenzofuran

It may also be used to prepare:

• 2-fluorobenzenesulfonamide
• methyl 2-{[(2-fluorophenyl)sulfonyl]amino}-5,6,7,8-tetrahydro-1-naphthalenecarboxylate
• potassium fluorobenzene-2-sulfonate
• 1-(2-bromobenzyl)-2-(2-fluorophenyl)pyrrole

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): 230.0 °F - closed cup
• Flash Point(C): 110 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves