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379506

Sigma-Aldrich

Tris(2,3-epoxypropyl) isocyanurate

Synonym(s):

1,3,5-Tris(oxiran-2-ylmethyl)-1,3,5-triazinane-2,4,6-trione, TGIC, Triglycidyl isocyanurate

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About This Item

Empirical Formula (Hill Notation):
C12H15N3O6
CAS Number:
2451-62-9
Molecular Weight:
297.26
EC Number:
219-514-3
MDL number:
MFCD00080670
UNSPSC Code:
12162002
PubChem Substance ID:
24863665
NACRES:
NA.23

form

powder

SMILES string

O=C1N(CC2CO2)C(=O)N(CC3CO3)C(=O)N1CC4CO4

InChI

1S/C12H15N3O6/c16-10-13(1-7-4-19-7)11(17)15(3-9-6-21-9)12(18)14(10)2-8-5-20-8/h7-9H,1-6H2

InChI key

OUPZKGBUJRBPGC-UHFFFAOYSA-N

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Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Muta. 1B - Skin Sens. 1 - STOT RE 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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M M Ames et al.
Cancer research, 44(9), 4151-4156 (1984-09-01)
Teroxirone is an experimental triepoxide antitumor agent currently undergoing evaluation in clinical trials. We have developed an assay based on derivatization with diethyldithiocarbamate followed by normal-phase high-performance liquid chromatographic analysis. When 14C-labeled teroxirone is administered to rabbits by rapid i.v.
L Meuleman et al.
Allergy, 54(7), 752-756 (1999-08-12)
The case is presented of a man with allergic contact dermatitis and occupational asthma due to triglycidylisocyanurate (TGIC), which is used as a hardener in thermosetting powder paint. The contact dermatitis was confirmed by patch testing (TGIC 0.5% and 5%
Martin Roff et al.
The Annals of occupational hygiene, 48(3), 257-265 (2004-04-03)
This paper describes workplace dermal exposure measurements that were carried out by the Health and Safety Laboratory as part of the EU RISKOFDERM project to measure dust contamination. Exposure to dry powder spray paints was measured at five sites on
U Erikstam et al.
Contact dermatitis, 44(1), 13-17 (2001-01-13)
Triglycidyl isocyanurate (TGIC) is mainly used in polyester-based powder paints, but also in laminates, insulating varnishes, coatings and adhesives. Several cases of contact allergy to TGIC have been reported during the last 10 years. Contact allergy to TGIC has developed
R Jolanki et al.
Contact dermatitis, 30(1), 12-15 (1994-01-01)
A 48-year-old female silk-screen printer had worked in the manufacture of circuit boards for 12 years before she got the first symptoms of dermatitis on her wrists and lower arms. On the 1st patch test session, epoxy resin and the
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