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125598

Sigma-Aldrich

1,4-Cyclohexanedimethanol

mixture of cis and trans, 99%

Synonym(s):

1,4-Bis(hydroxymethyl)cyclohexane, mixture of cis and trans

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About This Item

Linear Formula:
C6H10(CH2OH)2
CAS Number:
Molecular Weight:
144.21
Beilstein:
1902271
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

vapor density

5 (vs air)

Assay

99%

autoignition temp.

584 °F

bp

283 °C (lit.)

SMILES string

OCC1CCC(CO)CC1

InChI

1S/C8H16O2/c9-5-7-1-2-8(6-10)4-3-7/h7-10H,1-6H2

InChI key

YIMQCDZDWXUDCA-UHFFFAOYSA-N

General description

1,4-Cyclohexanedimethano is extensively used as cross-linking reagent in polymer industry.

Application

1,4-Cyclohexanedimethanol has been used in the synthesis of polyketal copolymers. It was used as diol comonomer during the synthesis of polyester-carbonates based on 1,3-propylene-co-1,4-cyclohexanedimethylene succinate.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

321.8 °F - closed cup

Flash Point(C)

161 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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New biodegradable polymers from renewable sources: Polyester-carbonates based on 1, 3-propylene-co-1, 4-cyclohexanedimethylene succinate.
Liu Y, et al.
Journal of Polymer Science Part A: Polymer Chemistry, 39(14), 2508-2519 (2001)
Mingliang Ding et al.
Biodegradation, 23(1), 127-132 (2011-07-07)
Enzymatic hydrolytic degradation of polybutylene succinate (PBS), poly(polybutylenesuccinate-co-1,4-cyclohexane dimethanol) (PBS/CHDM) and poly(polybutylene succinate-co-diglycolic acid) (PBS/DGA) in mixed solvent of tetrahydrofuran (THF) and toluene was examined. Lipase was used as catalyst to degrade polymers with molecular weight of more than 100,000
Stephen C Yang et al.
Bioconjugate chemistry, 19(6), 1164-1169 (2008-05-27)
Acute inflammatory diseases are a major cause of death in the world, and effective treatments are greatly needed. Macrophages play a central role in causing acute inflammatory diseases, and there is currently great interest in developing drug delivery vehicles that
Pingfan Li et al.
Chemical communications (Cambridge, England), (36)(36), 5412-5414 (2009-09-03)
The silica gel absorbed amino acid salt catalyzed asymmetric intramolecular Robinson annulation reaction has been developed; up to 97% ee was obtained with this readily recoverable organocatalyst.
Zehong Xiang et al.
Macromolecular bioscience, 19(8), e1900112-e1900112 (2019-06-22)
Inflammation-associated thrombosis is a non-negligible source of mortalities and morbidities worldwide. To manipulate inflammation-associated coagulation, nanoparticles that contain anti-inflammatory polymer (copolyoxalate containing vanillyl alcohol, PVAX) and anti-thrombotic heparin derivative deoxycholic acid (Hep-DOCA) are prepared. The strategy takes advantage of the

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