- First total synthesis and structural reassignment of (-)-aplysiallene.
First total synthesis and structural reassignment of (-)-aplysiallene.
Organic letters (2007-08-19)
Jian Wang, Brian L Pagenkopf
PMID17691801
초록
The first total synthesis of (-)-aplysiallene has been completed in 16 steps and features a key sequential Mukaiyama aerobic oxidative cyclization to prepare the fused bis-THF core. The original stereochemical assignment has been revised as shown.
MATERIALS