1302101

Guanfacine hydrochloride

United States Pharmacopeia (USP) Reference Standard

• 동의어(들): N (Aminoiminomethyl)-2,6-dichlorobenzeneacetamide
• 실험식(Hill 표기법): C₉H₉Cl₂N₃O · HCl
• CAS Number: 29110-48-3
• Molecular Weight: 282.55
• MDL number: MFCD00798230
• UNSPSC 코드: 41116107
• PubChem Substance ID: 329749977
• NACRES: NA.24

속성

• Grade: pharmaceutical primary standard
• API family: guanfacine
• 제조업체/상표: USP
• 응용 분야: pharmaceutical (small molecule)
• 형식: neat
• SMILES string: Cl.NC(=N)NC(=O)Cc1c(Cl)cccc1Cl
• InChI: 1S/C9H9Cl2N3O.ClH/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13;/h1-3H,4H2,(H4,12,13,14,15);1H
• InChI key: DGFYECXYGUIODH-UHFFFAOYSA-N
• 유전자 정보: human ... ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

설명

일반 설명

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

애플리케이션

• Reduction of Anxiety-related Reactivity in Primates: Guanfacine hydrochloride mediates anxiety-related reactivity and reduces associated agonistic behavior in two pigtail macaques, showcasing its potential for managing stress and aggression in clinical and veterinary settings (Hopper et al., 2024).


• Enhanced Analgesia for Surgical Procedures: The synergistic interaction of guanfacine with lidocaine enhances cutaneous analgesia, indicating its utility in improving pain management strategies, particularly in surgical environments (Chou et al., 2024).

생화학적/생리학적 작용

α-2 noradrenergic receptor agonist.

분석 메모

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

기타 정보

Sales restrictions may apply.

안전성 정보

• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable