822857

TSKgel^® SuperSW mAb HR (4 µm) HPLC Column

L x I.D. 4 cm × 6 mm, diol phase

• 동의어(들): TSKgel^® Size Exclusion (SW-Type) HPLC Guard Column
• UNSPSC 코드: 41115711

속성

• product name: TSKgel^® SuperSW mAb HR Guard Column, phase diol, L × I.D. 4 cm × 6 mm, 4 μm particle size
• material: stainless steel
• Agency: suitable for USP L20; suitable for USP L59
• 제품 라인: TSKgel^®
• 제조업체/상표: Tosoh SuperSW HR Guard, 22857
• 파라미터: ≤0.5 M salt concentration; 0-100% aqueous soluble organic solvents; 1 mL/min flow rate; 10-30 °C temperature
• 기술: HPLC: suitable
• 길이 × I.D.: 4 cm × 6 mm
• 기질: silica particle platform
• 기질 활성군: diol phase
• 입자 크기: 4 μm
• 공극 크기: 250 Å pore size
• 작동 pH: 2.5-7.5
• 분리 기술: size exclusion (SEC)

설명

일반 설명

The TSKgel SuperSW and UltraSW mAb columns consist of three specialized columns designed for the separation and analysis of monoclonal antibodies (mAb). While mAbs can be analyzed using many different modes of HPLC, size exclusion is best to determine the level of aggregation, dimer formation, and fragmentation, making it the best method for heterogeneity studies. TSKgel SuperSW mAb HR columns are optimized for high resolution analysis of mAb monomer and dimer; these 30 cm x 7.8 mm ID slica-based stainless steel columns offer reduced lot-to-lot variation, long column life, reduction of unspecified adsorption, and superior recovery of aggregates. The TSKgel SuperSW mAb columns utilize a unique pore-controlled technology, which produces a shallow calibration curve in the molecular weight region of a typical monoclonal antibody. The calibration curve for the TSKgel SuperSW mAb HR column is similar to that of the industry-leading TSKgel G3000SWxl column and has a shallower slope than the TSKgel UltraSW Aggregate column around the molecular weight range of gamma-globulin. This shallow calibration curve produces high resolution separations.

물리적 형태

Shipped in 0.05% NaN3 and 0.1 M Na2SO4 in 0.1 M phosphate buffer, pH 6.7.

추천 제품

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법적 정보

TSKgel is a registered trademark of Tosoh Corporation