추천 제품
product name
Astec® CHIROBIOTIC® TAG Chiral HPLC Column, 5 μm particle size, L × I.D. 10 cm × 2.1 mm
material
stainless steel column
Agency
suitable for USP L63
설명
HPLC column
제품 라인
Astec®
포장
pkg of 1 ea
제조업체/상표
Astec®
파라미터
0-45 °C temperature
241 bar pressure (3500 psi)
기술
HPLC: suitable
LC/MS: suitable
길이 × I.D.
10 cm × 2.1 mm
기질
High-purity silica gel particle platform
fully porous particle
기질 활성군
teicoplanin aglycone phase
입자 크기
5 μm
공극 크기
100 Å
operating pH range
3.0-6.8
분리 기술
chiral
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일반 설명
The removal of three carbohydrate moieties gives CHIROBIOTIC® TAG complementary selectivity to CHIROBIOTIC® T. Resolution is enhanced toward many of the amino acids, α, β, γ and cyclic, and especially sulfur-containing methionine, histidine and cysteine. A number of neutral molecules like the oxazolidinones, hydantoins and diazepines have shown enhanced resolution and, more remarkably, in the single solvents like methanol, ethanol and acetonitrile. Some acidic molecules have also shown increased selectivity.
- Bonded phase: Teicoplanin aglycone
- Operating pH range: 3.0 - 6.8
- Particle diameter: 5, 10 or 16 μm
- Pore size: 100 Å
법적 정보
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC
Choose from one of the most recent versions:
Adsorption behavior of a teicoplanin aglycone bonded stationary phase under harsh overload conditions
Journal of Chromatography A, 1154 (1-2), 2477-2286 (2007)
Journal of chromatography. A, 1061(2), 167-173 (2005-01-12)
We describe a new tandem-columns chiral-achiral HPLC arrangement by using a chiral column (CHIROBIOTIC TAG) connected in series with an achiral column (Spherisorb S5 SCX), based on a strong cationic exchange mechanism; this approach is very useful for the analysis
Journal of pharmaceutical and biomedical analysis, 50(1), 96-99 (2009-05-19)
A direct chiral high-performance liquid chromatography (HPLC) method was developed and validated for the resolution and quantification of antiepileptic drug enantiomers, R-(-)- and S-(+)-vigabatrin (gamma-vinyl-gamma-aminobutyric acid) in pharmaceutical products. The separation was optimized on a macrocyclic glycopeptide antibiotic chiral stationary
Journal of chromatography. A, 1236, 123-131 (2012-04-03)
Teicoplanin aglycone-based chromatography columns (Chirobiotic TAG) enable amino acid enantioseparation with aqueous mobile phases, which perfectly accommodates the distinct hydrophilicity of most amino acids. Therefore, this stationary phase constitutes a promising option in particular for preparative-scale separations that require high
Chemoenzymatic preparation of enantiopure l-benzofuranyl- and l-benzo[b]thiophenyl alanines
Tetrahedron Asymmetry, 19 (4), 500-511 (2008)
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