W3516

Anti-WSTF (C-Terminal) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 동의어(들): Anti-BAZ1B, Anti-Bromdomain Adjacent to Zn Finger Domain 1B, Anti-Williams Syndrome Transcription Factor, Anti-Williams-Beuren Syndrome Chromosome Region 9
• MDL number: MFCD08705535
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: antigen 175 kDa
• 종 반응성: human, mouse
• 기술: immunoprecipitation (IP): 5-10 μg using from lysates of HEK293-T cells; indirect immunofluorescence: 10-20 μg/mL using paraformaldehyde-fixed NIH3T3 cells; microarray: suitable; western blot: 0.5-1 μg/mL using extracts of MCF-7 breast cancer cell line
• UniProt 수납 번호: Q9UIG0
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... BAZ1B(9031) ; mouse ... Baz1b(22385) ; rat ... Baz1b(368002)

설명

일반 설명

Williams syndrome transcription factor (WSTF) belongs to the WAL/BAZ/WAC protein family, encoded by the bromodomain adjacent to zinc finger domain 1B (BAZ1B) gene. It is a non-secretory protein, which consists of a C-terminal bromodomain adjacent to a PHD (plant homeodomain) finger.

면역원

synthetic peptide corresponding to amino acids 1467-1483 of human WSTF, conjugated to KLH via an N-terminal added cysteine residue. The corresponding rat and mouse sequence differ from the immunizing sequence by three amino acids.

애플리케이션

Anti-WSTF (C-Terminal) antibody produced in rabbit has been used in western blotting and immunofluorescence.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

생화학적/생리학적 작용

Williams syndrome transcription factor (WSTF) is implicated in transcription, replication, chromatin remodeling and DNA damage response. It acts as a tyrosine protein kinase. Mutations in this gene are associated with Williams-Beuren syndrome. WSTF might function as an activator of gene expression of cytochrome P450 family 21 subfamily A member 2 (CYP21A2) and CYP19A1.

물리적 형태

Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)